ELOVL5
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Official Full Name
ELOVL fatty acid elongase 5 -
Overview
ELOVL5 plays a role in elongation of long-chain polyunsaturated fatty acids (Leonard et al., 2000 (PubMed;10970790)). -
Synonyms
ELOVL5;ELOVL fatty acid elongase 5;ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3 like, yeast);elongation of very long chain fatty acids protein 5;dJ483K16.1;HELO1;ELOVL FA elongase 5;fatty acid elongase 1;3-keto
Recombinant Proteins
- Zebrafish
- Rat
- Chicken
- Mouse
- Human
- Pongo Abelii
- Bovine
- Macaca fascicularis
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Xenopus laevis
- Mus musculus
- Mammalian Cells
- HEK293
- E.coli
- His
- Avi
- Fc
Involved Pathway
ELOVL5 involved in several pathways and played different roles in them. We selected most pathways ELOVL5 participated on our site, such as Fatty acid elongation,Biosynthesis of unsaturated fatty acids,Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELOVL5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of unsaturated fatty acids | HADHA,PTPLA,HADHAA,SCD,ACOX3,ACOX1,SCD5,SCDB,ACAA1A,FADS2 |
| Fatty acid metabolism | HSD17B12A,PPT1,PTPLAD2,HADHA,ACAA1A,HSD17B12,TECRB,CPT1B,CPT1A,FASN |
| Fatty acid elongation | PPT2,ELOVL4,ACOT1,ELOVL4B,ELOVL7,HSD17B12,HADHB,HADHAB,ACOT2,ACOT5 |
Protein Function
ELOVL5 has several biochemical functions, for example, fatty acid elongase activity,transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELOVL5 itself. We selected most functions ELOVL5 had, and list some proteins which have the same functions with ELOVL5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transferase activity | ZDHHC5A,RPS6KAL,GOT1L1,RAF1A,OXCT2B,HS3ST1L1,METTL7B,UGT5A2,DNMT3AB,PRDM13 |
Interacting Protein
ELOVL5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELOVL5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELOVL5.
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References
- Mabuchi, F; Sakurada, Y; et al. Involvement of Genetic Variants Associated With Primary Open-Angle Glaucoma in Pathogenic Mechanisms and Family History of Glaucoma. AMERICAN JOURNAL OF OPHTHALMOLOGY 159:437-444(2015).
- Kuah, MK; Jaya-Ram, A; et al. The capacity for long-chain polyunsaturated fatty acid synthesis in a carnivorous vertebrate: Functional characterisation and nutritional regulation of a Fads2 fatty acyl desaturase with Delta 4 activity and an Elovl5 elongase in striped snakehead (Channa striata). BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1851:248-260(2015).
