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Official Full Name elongation protein 4 homolog
Background Elongation protein 4 homolog (ELP4) is a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. Alternative names for ELP4 include elongator co
Synonyms ELP4; elongation protein 4 homolog (S. cerevisiae); C11orf19, chromosome 11 open reading frame 19; elongator complex protein 4; PAXNEB; hELP4; PAX6 neighbor gene protein; PAX6NEB; C11orf19; dJ68P15A.1; FLJ20498
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ELP4-12425H Recombinant Human ELP4, His-tagged E.coli His
    Human ELP4-3265H Recombinant Human ELP4 Protein, GST-tagged Wheat Germ GST
    Human ELP4-4560H Recombinant Human ELP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ELP4-623H Recombinant Human elongator acetyltransferase complex subunit 4, His-tagged E.coli His
    Human ELP4-6615HCL Recombinant Human ELP4 293 Cell Lysate HEK293 N/A
    Mouse Elp4-2806M Recombinant Mouse Elp4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ELP4-5156M Recombinant Mouse ELP4 Protein Mammalian Cell His
    Zebrafish ELP4-2408Z Recombinant Zebrafish ELP4 Mammalian Cell His

    ELP4 involved in several pathways and played different roles in them. We selected most pathways ELP4 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes SAP130; DNMT3A; PRDM16; EED; KANSL2; TADA3; PBRM1; SMARCB1A; MSL2B; KAT7
    Chromatin organization JMJD6; KDM4C; ING3; MBD3; PHF20B; SMARCA2; KDM7AB; BRPF1; CAPNS2; KDM3B
    HATs acetylate histones CCDC101; RBB4L; MSL1A; TADA2A; MSL3; BRPF3; KAT7; TADA2B; BRD1; TADA3

    ELP4 has several biochemical functions, for example, contributes_to RNA polymerase II core binding, contributes_to histone acetyltransferase activity, phosphorylase kinase regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ELP4 itself. We selected most functions ELP4 had, and list some proteins which have the same functions with ELP4. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to RNA polymerase II core binding IKBKAP; ELP3; ELP4; ELP2
    contributes_to histone acetyltransferase activity SAP130; TAF12; SUPT3H; KAT5; TADA2A; KAT2A; TADA1; TAF5L; TADA3; TAF9
    phosphorylase kinase regulator activity PRKAG2; ELP3; IKBKAP; ELP4
    protein binding MTMR6; ACTB; ABCG1; KIF1C; CTNNA3; NTS; MS4A1; RAB43; FZD3; FLAD1

    ELP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELP4.


    Hughes, LA; Gaston, J; et al. Electrospun fiber constructs for vocal fold tissue engineering: Effects of alignment and elastomeric polypeptide coating. ACTA BIOMATERIALIA 13:111-120(2015).
    Gkampeta, A; Fidani, L; et al. Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population. EPILEPSY RESEARCH 108:1734-1739(2014).

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