Recombinant Human ELP4 Protein, GST-tagged

• Cat.No.: ELP4-3265H
• Product Overview: Human ELP4 full-length ORF ( AAH12514.1, 1 a.a. - 535 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.1 kDa
• AA Sequence: MAAVATCGSVAASTGSAVATASKSN VTSFQRRGPRASVTNDSGPRLVSIA GTRPSVRNGQLLVSTGLPALDQLLG GGLAVGTVLLIEEDKYNIYSPLLFK YFLAEGIVNGHTLLVASAKEDPANI LQELPAPLLDDKCKKEFDEDVYNHK TPESNIKMKIAWRYQLLPKMEIGPV SSSRFGHYYDASKRMPQELIEASNW HGFFLPEKISSTLKVEPCSLTPGYT KLLQFIQNIIYEEGFDGSNPQKKQR NILRIGIQNLGSPLWGDDICCAENG GNSHSLTKFLYVLRGLLRTSLSACI ITMPTHLIQNKAIIARVTTLSDVVV GLESFIGSERETNPLYKDYHGLIHI RQIPRLNNLICDESDVKDLAFKLKR KLFTIEAGVQWHDLGSRRPRLLGSG GSPASASLVAGITGAHHHAQLIFVF LVEMGFHHVGQAGLELLTSGDSSAS ASQSAGIAGMSYRARPRALYFKENK SKVGARQLLETREEHLSSRLLILTQ AERLCMGRRFFTAFHIFNELPCKGD CICLQTCQTQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ELP4 elongation protein 4 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: ELP4
• Synonyms: ELP4; elongation protein 4 homolog (S. cerevisiae); C11orf19, chromosome 11 open reading frame 19; elongator complex protein 4; PAXNEB; hELP4; PAX6 neighbor gene protein; PAX6NEB; C11orf19; dJ68P15A.1; FLJ20498
• Gene ID: 26610
• mRNA Refseq: NM_019040
• Protein Refseq: NP_061913
• MIM: 606985
• UniProt ID: Q96EB1