EPHA5
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Official Full Name
EPH receptor A5
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Background
EPH receptor A5 (EPHA5); is a glycoprotein that is expressed by astrocytes and skeletal muscle. It provides guidance cues for retinal ganglion cells1 and is essential for proper retinal axon guidance and topographic mapping in the mammalian visual system. -
Synonyms
EPHA5; EPH receptor A5; ephrin type-A receptor 5; CEK7; EHK1; Hek7; TYRO4; EK7; EHK-1; EPH-like kinase 7; EPH homology kinase 1; Eph homology kinase-1; brain-specific kinase; receptor protein-tyrosine kinase HEK7; tyrosine-protein kinase receptor E;
- Involved Pathway
- Protein Function
- Interacting Protein
- EPHA5 Related Research Area
EPHA5 involved in several pathways and played different roles in them. We selected most pathways EPHA5 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | NRTN;CSK;COL6A1;MYL12B;DUSP4;KBTBD7;DCC;CSNK2B;Plxna2 |
EPHA5 has several biochemical functions, for example, ATP binding, GPI-linked ephrin receptor activity, ephrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHA5 itself. We selected most functions EPHA5 had, and list some proteins which have the same functions with EPHA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | DCLK3;INSRA;GUCY2C;MYO1G;cka1;DDX42;ABCB6;CDK5;PCXA |
| GPI-linked ephrin receptor activity | EPHA3;EPHA7;EK1;EPHA5;EPHA8;EPHA4 |
| ephrin receptor activity | EPHA4B;EPHA6;EPHB6;EPHA5;EPHB2B;EPHB3A;EPHB4A;EK1;EPHB4 |
| transmembrane-ephrin receptor activity | EFNA3;EFNB3;EPHB1;EPHA1;EPHB2;EPHA4;EFNA4;EPHA10;EPHA5 |
EPHA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHA5.
saicar; ephopt; PKM; purvalanol b
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