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Official Full Name family with sequence similarity 161, member A
Background This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.
Synonyms FAM161A; family with sequence similarity 161, member A; retinitis pigmentosa 28 (autosomal recessive) , RP28; protein FAM161A; FLJ13305; retinitis pigmentosa 28 (autosomal recessive); RP28; MGC129982; MGC129983
    • Species :
    • Human
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FAM161A-3714H Recombinant Human FAM161A Protein, GST-tagged Wheat Germ GST
    Human FAM161A-6418HCL Recombinant Human FAM161A 293 Cell Lysate HEK293 N/A
    Rat FAM161A-2224R Recombinant Rat FAM161A Protein Mammalian Cell His

    fam161a involved in several pathways and played different roles in them. We selected most pathways fam161a participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with fam161a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    fam161a has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fam161a itself. We selected most functions fam161a had, and list some proteins which have the same functions with fam161a. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ZFYVE20; NUP37; SREBF1; CENPP; NDUFS3; PRLR; TNNI3K; FASTKD5; GRIFIN; OTX1

    fam161a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fam161a here. Most of them are supplied by our site. Hope this information will be useful for your research of fam161a.

    CCDC102B; FSD2; EHMT2; CADPS; 80125

    Karlstetter, M; Sorusch, N; et al. Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. HUMAN MOLECULAR GENETICS 23:5197-5210(2014).
    Roosing, S; Lamers, IJC; et al. Disruption of the Basal Body Protein POC1B Results in Autosomal-Recessive Cone-Rod Dystrophy. AMERICAN JOURNAL OF HUMAN GENETICS 95:131-142(2014).

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