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FBXL20

  • Official Full Name

    F-box and leucine-rich repeat protein 20

  • Overview

    Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
  • Synonyms

    FBXL20; F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 20; Fbl2; Fbl20; MGC15482; F-box protein FBL2; FLJ21037; DKFZp564O2364;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FBXL20-3899H Recombinant Human FBXL20 Protein, GST-tagged Wheat Germ GST
Human FBXL20-12778H Recombinant Human FBXL20, His-tagged E.coli His C-term-357a.a.
Human FBXL20-4969HF Recombinant Full Length Human FBXL20 Protein, GST-tagged In Vitro Cell Free System GST 436 amino acids
Mouse FBXL20-5720M Recombinant Mouse FBXL20 Protein Mammalian Cell His
Mouse FBXL20-3145M Recombinant Mouse FBXL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse FBXL20-3145M-B Recombinant Mouse FBXL20 Protein Pre-coupled Magnetic Beads HEK293
Rat FBXL20-2287R Recombinant Rat FBXL20 Protein Mammalian Cell His
Rat FBXL20-1944R-B Recombinant Rat FBXL20 Protein Pre-coupled Magnetic Beads HEK293
Rat FBXL20-1944R Recombinant Rat FBXL20 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FBXL20 Related Articles

FBXL20 involved in several pathways and played different roles in them. We selected most pathways FBXL20 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

FBXL20 has several biochemical functions, for example, contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL20 itself. We selected most functions FBXL20 had, and list some proteins which have the same functions with FBXL20. You can find most of the proteins on our site.

Function Related Protein
contributes_to ubiquitin protein ligase activityCUL1B;FBXL15;FBXL12;FBXL20;FBXL3;FBXL3A;FBXL6;CUL2;MED11

FBXL20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL20 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL20.

Xiao, J; Zhang, T; et al. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. GENES & DEVELOPMENT 29:184-196(2015).
Zhu, JJ; Deng, SS; et al. FBXL20 acts as an invasion inducer and mediates E-cadherin in colorectal adenocarcinoma. ONCOLOGY LETTERS 7:2185-2191(2014).
  • Q&As
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