Recombinant Human FBXL20 Protein, GST-tagged

• Cat.No.: FBXL20-3899H
• Product Overview: Human FBXL20 full-length ORF ( AAH07557, 1 a.a. - 436 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.7 kDa
• AA Sequence: MRRDVNGVTKSRFEMFSNSDEAVIN KKLPKELLLRIFSFLDVVTLCRCAQ VSRAWNVLALDGSNWQRIDLFDFQR DIEGRVVENISKRCGGFLRKLSLRG CLGVGDNALRTFAQNCRNIEVLNLN GCTKTTDATCTSLSKFCSKLRHLDL ASCTSITNMSLKALSEGCPLLEQLN ISWCDQVTKDGIQALVRGCGGLKAL FLKGCTQLEDEALKYIGAHCPELVT LNLQTCLQITDEGLITICRGCHKLQ SLCASGCSNITDAILNALGQNCPRL RILEVARCSQLTDVGFTTLARNCHE LEKMDLEECVQITDSTLIQLSIHCP RLQVLSLSHCELITDDGIRHLGNGA CAHDQLEVIELDNCPLITDASLEHL KSCHSLERIELYDCQQITRAGIKRL RTHLPNIKVHAYFAPVTPPPSVGGS RQRFCRCCIIL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FBXL20 F-box and leucine-rich repeat protein 20 [ Homo sapiens ]
• Official Symbol: FBXL20
• Synonyms: FBXL20; F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 20; Fbl2; Fbl20; MGC15482; F-box protein FBL2; FLJ21037; DKFZp564O2364
• Gene ID: 84961
• mRNA Refseq: NM_001184906
• Protein Refseq: NP_001171835
• MIM: 609086
• UniProt ID: Q96IG2