Fgd2

  • Official Full Name

    FYVE, RhoGEF and PH domain containing 2

Recombinant Proteins

  • Rhesus macaque
  • Mouse
  • Human
  • Mammalian Cells
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Avi
  • Fc
  • DDK
  • Myc
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
FGD2-1691R Recombinant Rhesus monkey FGD2 Protein, His-tagged Mammalian Cells Rhesus macaque His
FGD2-5832M Recombinant Mouse FGD2 Protein Mammalian Cells Mouse His
FGD2-6254HCL Recombinant Human FGD2 293 Cell Lysate HEK293 Human Non
FGD2-1513R Recombinant Rhesus Macaque FGD2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
FGD2-1513R-B Recombinant Rhesus Macaque FGD2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
FGD2-2709H Recombinant Human FGD2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
Fgd2-2991M Recombinant Mouse Fgd2 Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
FGD2-3221M Recombinant Mouse FGD2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
FGD2-3221M-B Recombinant Mouse FGD2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FGD2-4089H Recombinant Human FGD2 Protein, GST-tagged Wheat Germ Human GST
FGD2-4786HF Recombinant Full Length Human FGD2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 655 amino acids

    Involved Pathway

    Fgd2 involved in several pathways and played different roles in them. We selected most pathways Fgd2 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fgd2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    G alpha (12/13) signalling events TIAM2,NET1,ITSN1,DCLRE1B,KALRNB,ARHGEF1A,KALRN,FGD4A,ARHGEF17,ABR
    GPCR downstream signaling FGD4,SST,LPAR2B,ARHGEF16,RGS7,CCR3,ADORA3,ABR,QRFP,OR7D2
    Signal Transduction UTS2D,NOXO1A,OR7D2,OXGR1A.1,PENKA,DLC1,SH2B3,MDKA,GPR55A,GPR31
    Rho GTPase cycle ARHGAP10,ARHGAP9,ARHGAP25,ARHGAP17B,ARHGAP12,AKAP13,DLC1,MYO9B,FGD4A,ARHGAP12B
    Cell death signalling via NRAGE, NRIF and NADE FGD4A,PLEKHG2,BCL2L11,ARHGEF16,MCF2L,TIAM2,KALRN,FGD4,ARHGAP4,ARHGAP4A
    NRAGE signals death through JNK ARHGEF16,ARHGEF3,ABR,TIAM2,AKAP13,OBSCN,ARHGEF18A,ARHGEF1A,ARHGEF17,NET1
    Signaling by Rho GTPases ARHGAP19,RHOJ,CIT,DEPDC1B,OPHN1,RHOT1A,IQGAP3,DLC1,ARHGAP32,GDI1
    Signaling by GPCR ZFPM2B,OR7D2,GPR77,RGS14,TAAR1,ACKR4,RGS6,PYYA,RGS20,RAMP3

    Protein Function

    Fgd2 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity,guanyl-nucleotide exchange factor activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fgd2 itself. We selected most functions Fgd2 had, and list some proteins which have the same functions with Fgd2. You can find most of the proteins on our site.

    Function Related Protein
    guanyl-nucleotide exchange factor activity PTGIR,TAGAP,DOCK4,DOCK6,RIC8,FLCN,DOCK5,SH2D3C,DENND5B,FGD6
    small GTPase binding PEX5L,TSC2,FGD1,FGD6,PEX5,GDI2,ERRFI1,FLNA,RCC2,FGD3
    Rho guanyl-nucleotide exchange factor activity ARHGEF7,ARHGEF9B,ARHGEF1A,RASGRF2B,FGD3,ALS2CL,ARHGEF11,KALRNB,ARHGEF18A,FGD4
    metal ion binding ZFP580,DNAJA4,ZNF395,PMELA,KLF9,ZNF669,NR1D2B,ZUFSP,HPDL,PDE3B
    protein binding FRG1,HPSE,BAIAP2L1,GEMIN8,ARL6IP4,TERT,SLC3A2,PKN3,CHMP1B,PROP1

    Interacting Protein

    Fgd2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fgd2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fgd2.

    KLHL12;TMEM239;RNPS1

    Resources

    References

    • Hasler, R; Kerick, M; et al. Alterations of pre-mRNA splicing in human inflammatory bowel disease. EUROPEAN JOURNAL OF CELL BIOLOGY 90:603-611(2011).
    • Cerda-Reverter, JM; Agulleiro, MJ; et al. Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors. GENERAL AND COMPARATIVE ENDOCRINOLOGY 188:133-136(2013).

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