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FHL1

  • Official Full Name

    four and a half LIM domains 1

  • Overview

    This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
  • Synonyms

    FHL1; four and a half LIM domains 1; four and a half LIM domains protein 1; bA535K18.1; FHL1B; FLH1A; KYO T; LIM protein SLIMMER; MGC111107; SLIM1; XMPMA; FHL 1; FHL 1B; FHL-1; FHL1 protein; FHL1_HUMAN; FHL1A; Four and a half Lin11 Isl 1 and Mec 3 domains 1; RAM14-1; RBP associated molecule 14-1; Skeletal muscle LIM protein 1; Skeletal muscle LIM-protein 1; SLIM 1; SLIM; SLIM-1; SLIMMER; OTTHUMP00000024097; OTTHUMP00000024098; OTTHUMP00000024099; OTTHUMP00000024100; OTTHUMP00000024101; OTTHUMP00000024102; OTTHUMP00000024103; OTTHUMP00000024104; OTTHUMP00000024106; OTTHUMP00000024107; skeleta; KYOT;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human cells
  • Mamanlian cells
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FHL1-12888H Recombinant Human FHL1, GST-tagged E.coli GST 1-280a.a.
Human FHL1-28103TH Recombinant Human FHL1 protein, GST-tagged Wheat Germ GST
Human FHL1-28893TH Recombinant Human FHL1 Wheat Germ N/A 98 amino acids
Human FHL1-128H Recombinant Human FHL1, MYC/DDK-tagged HEK293 Myc/DDK
Human FHL1-6225HCL Recombinant Human FHL1 293 Cell Lysate HEK293 N/A
Human FHL1-1688HFL Recombinant Full Length Human FHL1 Protein, C-Flag-tagged Mammalian cells Flag
Human FHL1-151H Recombinant Human FHL1 Protein, His-tagged Human cells His
Human FHL1-4604HFL Recombinant Full Length Human FHL1, Flag-tagged Mamanlian cells Flag
Human FHL1-1142H Recombinant Human FHL1 protein, His-tagged E.coli His 2-323aa
Human FHL1-914H Recombinant Human FHL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FHL1-914H-B Recombinant Human FHL1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Fhl1-3011M Recombinant Mouse Fhl1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein

FHL1 involved in several pathways and played different roles in them. We selected most pathways FHL1 participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FHL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Jak-STAT signaling pathwayIfna11;CSH;IFNA12;IL11RA2;PIK3CG;Ifnlr1;STAT1;CSH1;Il6ra

FHL1 has several biochemical functions, for example, ion channel binding, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL1 itself. We selected most functions FHL1 had, and list some proteins which have the same functions with FHL1. You can find most of the proteins on our site.

Function Related Protein
ion channel bindingSCN3B;TRPC1;FGF13;CALM1;KCNQ3;ANK2;EPN1;CAV1;LRRK2
molecular_functionGPR62;GPR137B;ACTBL2;FAM167AB;C1QTNF3;PTMAA;GAN;ASB10;MRGPRA7
protein bindingPUS7L;PIH1D1;LNPEP;TYK2;VPS33B;CHRDL2;BAZ1B;TEC;MYEF2
zinc ion bindingADAM28;MSL2A;TRIM42;Car8;POLE;GTF2H2;SNAI1A;APOBEC3B;CAHZ

FHL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL1.

NRIP1; AKAP12; PRNP; SRPK1; ESR1; EPB41; MCC; HLA-B; IKBKE; PRKAB1; DEAF1; EED; ENO1; ZNF16

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