Recombinant Human FHL1, GST-tagged

• Cat.No.: FHL1-12888H
• Product Overview: Recombinant Human FHL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-280a.a.
• Description: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FHL1 four and a half LIM domains 1 [ Homo sapiens ]
• Official Symbol: FHL1
• Synonyms: FHL1; four and a half LIM domains 1; four and a half LIM domains protein 1; bA535K18.1; FHL1B; FLH1A; Four and a half LIM domains 1; KYO T; LIM protein SLIMMER; MGC111107; SLIM1; XMPMA; skeletal muscle LIM-protein1; skeletal muscle LIM-protein 1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYOT; SLIM; FHL-1; FHL1A; SLIM-1; SLIMMER
• Gene ID: 2273
• mRNA Refseq: NM_001159699
• Protein Refseq: NP_001153171
• MIM: 300163
• UniProt ID: Q13642
• Chromosome Location: Xq26.3
• Pathway: Delta-Notch Signaling Pathway, organism-specific biosystem
• Function: metal ion binding; molecular_function; protein binding; zinc ion binding