| Species : |
Human |
| Source : |
CHO |
| Description : |
Flt3-L (Flt3 Ligand) is a membrane protein, homologous to SCF and M-CSF, that stimulates early hematopoietic cytokines. In vivo and ex vivo tests have confirmed that Flt3-L can regulate the proliferation and differentiation of non-erythroid hematopoietic stem/progenitor cells. In synergy with various cytokines, Flt3-L can promote the proliferation, differentiation and maturation of pre-B lymphocytes, dendritic cells (DC), natural killer (NK) cells, and cytotoxic T lymphocytes (CTL), and thus has important anti-tumor effects. |
| Form : |
Lyophilized powder |
| Endotoxin : |
<20 EU/mg |
| Bio-activity : |
>1.0 x 10^6 IU/mg |
| Purity : |
>95.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE. |
| Storage Buffer : |
10mM Phosphate-Buffered Saline (pH 7.2) |
| Storage : |
Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing. |
| Sterility : |
Sterility |
| Instructions : |
It is recommended that lyophilized GMP rhFlt3L be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration. |