fmnl3 Protein, formin-like 3


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Official Full Name formin-like 3
Background The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein. Two alternative transcripts encoding different isoforms have been described.
Synonyms FMNL3; formin-like 3; formin-like protein 3; DKFZp762B245; MGC45819; WBP3; WW domain binding protein 3; WW domain-binding protein 3; formin homology 2 domain-containing protein 3; FHOD3; WBP-3; FLJ45265
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FMNL3-2435H Recombinant Human FMNL3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human FMNL3-4391H Recombinant Human FMNL3 Protein, GST-tagged Wheat Germ GST
    Human FMNL3-659HCL Recombinant Human FMNL3 cell lysate N/A
    Mouse FMNL3-5936M Recombinant Mouse FMNL3 Protein Mammalian Cell His

    fmnl3 involved in several pathways and played different roles in them. We selected most pathways fmnl3 participated on our site, such as Downregulation of ERBB2:ERBB3 signaling, Endocytosis, ErbB2/ErbB3 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with fmnl3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Downregulation of ERBB2:ERBB3 signaling RNF41; FMNL3; NRG2A
    Endocytosis SNX5; DAB2; IST1; CHMP4B; SH3GLB1B; CAPZA2; WIPF1A; PIP5K1BB; HLA-E; WAS
    ErbB2/ErbB3 signaling events FMNL3; RNF41; DOCK7; CHRNE; CHRNA1
    Internalization of ErbB1 RNF103-CHMP3; ZFYVE28; FMNL3; SPRY2; STAMBP
    Regulation of FZD by ubiquitination FMNL3; RSPO4; LGR6; RSPO1; RSPO3; LGR5; LGR4; RNF43; RSPO2; ZNRF3
    Signal Transduction DNER; NOXA1; NMBB; DRAP1; RNF31; DEPDC7; GHRB; NRP2A; NOG; OR56A1
    Signaling by ERBB2 FMNL3; CUL5A
    Signaling by Wnt FMNL3; RSPO4; TMED5; SOX7; C; KLHL12; KREMEN2; HECW1; RSPO1; SOX6

    fmnl3 has several biochemical functions, for example, SH3 domain binding, cysteine-type endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by fmnl3 itself. We selected most functions fmnl3 had, and list some proteins which have the same functions with fmnl3. You can find most of the proteins on our site.

    Function Related Protein
    SH3 domain binding NCF1; CASP9; SGIP1; ADAM17; PLSCR1; PAK3; GJA1; UVRAG; SH3BGRL; OSTF1
    cysteine-type endopeptidase activity USP51; CASPBL; USP10; USP14; CTSL.1; CTSH; CASP6; USP47; USP8; USP48
    protein binding EXOC3; PIK3C2B; MUC5B; SULT1B1; LMO1; BATF; S100A10; WDR25; FBXO27; PAG1
    ubiquitin-specific protease activity ATXN3L; OTUD6A; USP51; COPS5; USP16; USP42; OTUD1; USP18; STAMBP; USP20

    fmnl3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fmnl3 here. Most of them are supplied by our site. Hope this information will be useful for your research of fmnl3.

    Dlg4; PRPF40A

    Gauvin, TJ; Young, LE; et al. The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion. MOLECULAR BIOLOGY OF THE CELL 26:467-477(2015).
    Wakayama, Y; Fukuhara, S; et al. Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish. DEVELOPMENTAL CELL 32:109-122(2015).

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