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FOXQ1

Official Full Name

forkhead box Q1
Overview

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called;the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation,;tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 (PubMed 11747606)).
Synonyms

FOXQ1; forkhead box Q1; forkhead box protein Q1; HFH1; FOX Q1; FOXQ 1; FOXQ1_HUMAN; Hepatocyte nuclear factor 3 forkhead; Hepatocyte nuclear factor 3 forkhead homolog 1; HFH 1; HFH-1; HNF 3/forkhead like protein 1; HNF-3/forkhead-like protein 1; HNF3/forkhead like protein 1; MGC77469; Q1; Winged helix / forkhead transcription factor; Winged helix/forkhead transcription factor; zgc:77469;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	FOXQ1-6144HCL	Recombinant Human FOXQ1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	FOXQ1-2158H	Recombinant Human FOXQ1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	FOXQ1-4477H	Recombinant Human FOXQ1 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Mouse	FOXQ1-6014M	Recombinant Mouse FOXQ1 Protein	Mammalian Cell	His	Inquiry
Mouse	FOXQ1-3340M-B	Recombinant Mouse FOXQ1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	FOXQ1-3340M	Recombinant Mouse FOXQ1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	Foxq1-3081M	Recombinant Mouse Foxq1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rat	FOXQ1-2390R	Recombinant Rat FOXQ1 Protein	Mammalian Cell	His	Inquiry
Rat	FOXQ1-2046R-B	Recombinant Rat FOXQ1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	FOXQ1-2046R	Recombinant Rat FOXQ1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein
FOXQ1 Related Articles

FOXQ1 involved in several pathways and played different roles in them. We selected most pathways FOXQ1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXQ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

FOXQ1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXQ1 itself. We selected most functions FOXQ1 had, and list some proteins which have the same functions with FOXQ1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II transcription factor activity, sequence-specific DNA binding	ZSCAN18;ETV5A;SP3A;NFIB;TAL2;FOXP3A;FOXH1;ZNF202;SP1
sequence-specific DNA binding	HOXC12B;NR2C2;RX3;GATAD1;FOXN3;HOXC6A;CENPB;PAX3A;MKXB

FOXQ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXQ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXQ1.

Dlg4

Meng, FY; Speyer, CL; et al. PDGFR alpha and beta Play Critical Roles in Mediating Foxq1-Driven Breast Cancer Stemness and Chemoresistance. CANCER RESEARCH 75:584-593(2015).

Zhang, J; Yang, Y; et al. Double-Negative Feedback Loop Between MicroRNA-422a and Forkhead Box (FOX)G1/Q1/E1 Regulates Hepatocellular Carcinoma Tumor Growth and Metastasis. HEPATOLOGY 61:561-573(2015).