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FUK

Official Full Name

fucokinase
Overview

The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date.
Synonyms

FUK; fucokinase; L-fucose kinase; FLJ39408; L fucose kinase; FUK_HUMAN; OTTHUMP00000082728; OTTHUMP00000082729; 1110046B12Rik;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	FUK-13033H	Recombinant Human FUK, His-tagged	E.coli	His	695-1084a.a.	$319 / 25ug
Human	FUK-676HCL	Recombinant Human FUK cell lysate		N/A		Inquiry
Human	FUK-2660H	Recombinant Human FUK Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	FUK-4547H	Recombinant Human FUK Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	FUK-5136HF	Recombinant Full Length Human FUK Protein, GST-tagged	In Vitro Cell Free System	GST	1084 amino acids	Inquiry

Involved Pathway
Protein Function
Interacting Protein
FUK Related Articles

FUK involved in several pathways and played different roles in them. We selected most pathways FUK participated on our site, such as Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, GDP-L-fucose biosynthesis II (from L-fucose), which may be useful for your reference. Also, other proteins which involved in the same pathway with FUK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Amino sugar and nucleotide sugar metabolism	GPI;HKDC1;FUK;UGP2A;PGM3;GALT;GKUP;GMPPAB;HK1
Fructose and mannose metabolism	AKR1B1L;ALDOAB;GMDS;DHRS13L1;PFKL;Akr1b3;FUK;AKR1B7;HK1
GDP-L-fucose biosynthesis II (from L-fucose)
Metabolic pathways	LSS;DAK;TREH;COX11;CKB;NT5C2;CERS4;EXT1C;PIK3C2G

FUK has several biochemical functions, for example, ATP binding, fucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUK itself. We selected most functions FUK had, and list some proteins which have the same functions with FUK. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	SNRK;BMPR1B;SCN8A;ACSL1;KIF25;MYHZ1.1;PKN1B;PRKD2;ABCA1
fucokinase activity

FUK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUK here. Most of them are supplied by our site. Hope this information will be useful for your research of FUK.

Zou, YN; Kim, D; et al. Application of LDH-Release Assay to Cellular-Level Evaluation of the Toxic Potential of Harmful Algal Species. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77:345-352(2013).

Mendez-Vigo, B; Martinez-Zapater, JM; et al. The Flowering Repressor SVP Underlies a Novel Arabidopsis thaliana QTL Interacting with the Genetic Background. PLOS GENETICS 9:-(2013).