Recombinant Human FUK Protein, GST-tagged

• Cat.No.: FUK-4547H
• Product Overview: Human FUK full-length ORF ( NP_659496.2, 1 a.a. - 1084 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 144 kDa
• AA Sequence: MEQPKGVDWTVIILTCQYKDSVQVF QRELEVRQKREQIPAGTLLLAVEDP EKRVGSGGATLNALLVAAEHLSARA GFTVVTSDVLHSAWILILHMGRDFP FDDCGRAFTCLPVENPEAPVEALVC NLDCLLDIMTYRLGPGSPPGVWVCS TDMLLSVPANPGISWDSFRGARVIA LPGSPAYAQNHGVYLTDPQGLVLDI YYQGTEAEIQRCVRPDGRVPLVSGV VFFSVETAERLLATHVSPPLDACTY LGLDSGARPVQLSLFFDILHCMAEN VTREDFLVGRPPELGQGDADVAGYL QSARAQLWRELRDQPLTMAYVSSGS YSYMTSSASEFLLSLTLPGAPGAQI VHSQVEEQQLLAAGSSVVSCLLEGP VQLGPGSVLQHCHLQGPIHIGAGCL VTGLDTAHSKALHGRELRDLVLQGH HTRLHGSPGHAFTLVGRLDSWERQG AGTYLNVPWSEFFKRTGVRAWDLWD PETLPAEYCLPSARLFPVLHPSREL GPQDLLWMLDHQEDGGEALRAWRAS WRLSWEQLQPCLDRAATLASRRDLF FRQALHKARHVLEARQDLSLRPLIW AAVREGCPGPLLATLDQVAAGAGDP GVAARALACVADVLGCMAEGRGGLR SGPAANPEWMRPFSYLECGDLAAGV EALAQERDKWLSRPALLVRAARHYE GAGQILIRQAVMSAQHFVSTEQVEL PGPGQWVVAECPARVDFSGGWSDTP PLAYELGGAVLGLAVRVDGRRPIGA RARRIPEPELWLAVGPRQDEMTVKI VCRCLADLRDYCQPHAPGALLKAAF ICAGIVHVHSELQLSEQLLRTFGGG FELHTWSELPHGSGLGTSSILAGTA LAALQRAAGRVVGTEALIHAVLHLE QVLTTGGGWQDQVGGLMPGIKVGRS RAQLPLKVEVEEVTVPEGFVQKLND HLLLVYTGKTRLARNLLQDVLRSWY ARLPAVVQNAHSLVRQTEECAEGFR QGSLPLLGQCLTSYWEQKKLMAPGC EPLTVRRMMDVLAPHVHGQSLAGAG GGGFLYLLTKEPQQKEALEAVLAKT EGLGNYSIHLVEVDTQGLSLKLLGT EASTCCPFP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FUK fucokinase [ Homo sapiens ]
• Official Symbol: FUK
• Synonyms: FUK; fucokinase; L-fucose kinase; FLJ39408; L fucose kinase; 1110046B12Rik
• Gene ID: 197258
• mRNA Refseq: NM_145059
• Protein Refseq: NP_659496
• MIM: 608675
• UniProt ID: Q8N0W3