fut9

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fut9

Official Full Name FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) [ Homo sapiens ]
Background The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection.
Synonyms Fut9; mFUT9; AI746471; AU067636; mFuc-TIX; alpha-(1,3)-fucosyltransferase 9; fuc-TIX; fucT-IX; fucosyltransferase IX; galactoside 3-L-fucosyltransferase
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FUT9-13048H Recombinant Human FUT9, GST-tagged E.coli GST
    Human FUT9-219H Recombinant Human FUT9 protein CHO N/A
    Human FUT9-26H Recombinant Human FUT9, His-tagged HEK293 His
    Human FUT9-4569H Recombinant Human FUT9 Protein, GST-tagged Wheat Germ GST
    Human FUT9-6111HCL Recombinant Human FUT9 293 Cell Lysate HEK293 N/A
    Mouse Fut9-3291M Recombinant Mouse Fut9, His-tagged E.Coli or Yeast His
    Mouse FUT9-6096M Recombinant Mouse FUT9 Protein Mammalian Cell His
    Rat FUT9-2416R Recombinant Rat FUT9 Protein Mammalian Cell His
    Rhesus Macaque FUT9-1770R Recombinant Rhesus monkey FUT9 Protein, His-tagged Mammalian Cell His
    Chicken FUT9-3541C Recombinant Chicken FUT9 Mammalian Cell His

    fut9 involved in several pathways and played different roles in them. We selected most pathways fut9 participated on our site, such as Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with fut9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosphingolipid biosynthesis - globo series B3GALNT1; HEXB; ST3GAL2; NAGA; A4GALT; FUT9; FUT9A; ST8SIA1; ST3GAL1; FUT1
    Glycosphingolipid biosynthesis - lacto and neolacto series FUT5; FUT7; FUT1; B4GALT2; FUT9; B3GNT3; B3GNT1; B3GALT1; ST3GAL4; ABO
    Metabolic pathways PIPOX; GGPS1; NDST2; EXTL3; ACADM; AANAT2; AGLA; DEGS2; POLD1; BPNT1
    Other types of O-glycan biosynthesis POFUT1; B4GALT3; ST6GAL2; FUT9A; LFNG; RFNG; ST6GAL1; ST6GAL2A; B3GALTL; POMT1
    terminal O-glycans residues modification GCNT3; FUT9

    fut9 has several biochemical functions, for example, alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by fut9 itself. We selected most functions fut9 had, and list some proteins which have the same functions with fut9. You can find most of the proteins on our site.

    Function Related Protein
    alpha-(1->3)-fucosyltransferase activity FUT3; FUT11; UGGT1; FUT7; POMGNT2; GALNT18A; GTDC2; B3GNT8; B3GNT9-PS; DPY19L4
    fucosyltransferase activity FUT7; POFUT1; POMGNT2; 4931440L10Rik; FT1; GTDC2; FUT6; DPY19L4; FUT9B; GLT8D1

    fut9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with fut9 here. Most of them are supplied by our site. Hope this information will be useful for your research of fut9.

    ZDHHC17; TSSK3

    Itokazu, Y; Yu, RK; et al. Amyloid beta-Peptide 1-42 Modulates the Proliferation of Mouse Neural Stem Cells: Upregulation of Fucosyltransferase IX and Notch Signaling. MOLECULAR NEUROBIOLOGY 50:186-196(2014).
    Li, J; Yang, J; et al. Efficient Generalized Least Squares Method for Mixed Population and Family-based Samples in Genome-wide Association Studies. GENETIC EPIDEMIOLOGY 38:430-438(2014).

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