GATA5 Protein


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Official Full Name GATA binding protein 5
Background The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Synonyms GATA5; GATA binding protein 5; transcription factor GATA-5; bB379O24.1; GATA-binding factor 5; GATA5_HUMAN; GATA binding factor-5; GATA-binding protein 5;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)-Avi
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse GATA5-6226M Recombinant Mouse GATA5 Protein Mammalian Cell His Inquiry
    Chicken GATA5-6972C Recombinant Chicken GATA5 Mammalian Cell His Inquiry
    Zebrafish GATA5-8834Z Recombinant Zebrafish GATA5 Mammalian Cell His Inquiry
    Mouse Gata5-1567M Recombinant Mouse Gata5 Protein, His-tagged E.coli N-His Inquiry
    Rat Gata5-1568R Recombinant Rat Gata5 Protein, His-tagged E.coli N-His Inquiry
    Mouse GATA5-3484M Recombinant Mouse GATA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human GATA5-5470HF Recombinant Full Length Human GATA5 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Human GATA5-4751H Recombinant Human GATA5 Protein, GST-tagged Wheat Germ GST Inquiry

    GATA5 involved in several pathways and played different roles in them. We selected most pathways GATA5 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Factors involved in megakaryocyte development and platelet production AKAP1; GATA1A; GATA1; HBB-Y; KIF2B; ITPK1; HBD; BA2; MAFG; EHD1
    Hemostasis EHD1; G6b; CABLES1; KIFAP3; RAPGEF3; DOK2; ANXA2; AKAP10; CLEC1B; CD177

    GATA5 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA5 itself. We selected most functions GATA5 had, and list some proteins which have the same functions with GATA5. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding PBX1B; HLFB; ZNF302; ADAR; MAFBB; HOXC13B; ZNF789; ZNF497; PBRM1; TERF1
    RNA polymerase II regulatory region sequence-specific DNA binding SOX13; ZMYND11; STAT4; ZSCAN2; FOXD3; NFKB1; ARID5B; HMX1; ZGLP1; ZBTB4
    RNA polymerase II transcription factor binding GATA3; SPI1; HCLS1; ID4; KDM1A; GATA5; SPOP; CHST13; GATA1; DHX9
    chromatin binding TBL1Y; MKRN1; CEBPB; NSD1; KDM1A; BAZ1B; EGFR; FOSL2; ARID5A; OVOL2
    enhancer sequence-specific DNA binding ISL1; MYT1; GATA1; XBP1; TWIST1B; SOX9; FOXN4; GATA3; LDB1; KLF6A
    metal ion binding PDE3A; ZFP668; KLF12A; RPS6KAL; ZNF23; CYP2AD2; TRIM35-39; ZBED6; ZFPM1; ARSI
    protein binding RIPK2; YY1AP1; KLC3; NDUFS7; FMR1; AKAP12; CDX4; TINAGL1; MYOZ2; BAP1
    sequence-specific DNA binding NFIL3-4; HOXB5A; ISX; ZNF192; SOX21B; TCF7L2; Ar; FOXB1A; HDAC2; PRRX2
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding PKNOX1; CREB1; PTH; NFATC1; SPI1; RFX3; BHLHE40; RELA; SNAI2; HNF1B
    transcription factor activity, sequence-specific DNA binding ZBTB48; SOX1; NCOR1; ZNF624; ZNF613; ZIC5; MYNN; RUNX3; DMRT1; STAT1B
    transcription regulatory region DNA binding ARID5B; XBP1; BASP1; GLIS2; SMAD4; HINFP; TRP53; MTERFD3; CREB3L2; MLL1
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding OVOL2; SOX17; GATA1; ONECUT3; AIRE; MAFB; PKNOX1; GATA2; ATF1; PAX9
    zinc ion binding NR6A1A; RABGEF1; MMP25; MMP1A; GATAD2AB; MT2; EHMT2; TRIM55; PTGR1; CA4

    GATA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA5.

    Zhang, XL; Dai, N; et al. GATA5 loss-of-function mutation in familial dilated cardiomyopathy. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 35:763-770(2015).
    Wang, J; Mao, JH; et al. A Novel NKX2.6 Mutation Associated with Congenital Ventricular Septal Defect. PEDIATRIC CARDIOLOGY 36:646-656(2015).

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