GATA5 Protein

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GATA5

Official Full Name	GATA binding protein 5
Background	The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Synonyms	GATA5; GATA binding protein 5; transcription factor GATA-5; bB379O24.1; GATA-binding factor 5; GATA5_HUMAN; GATA binding factor-5; GATA-binding protein 5;

Type:
Recombinant Proteins

Species :
Chicken
Human
Mouse
Rat
Zebrafish

Source :
E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)-Avi
N-His

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	GATA5-6226M	Recombinant Mouse GATA5 Protein	Mammalian Cell	His	Inquiry
Chicken	GATA5-6972C	Recombinant Chicken GATA5	Mammalian Cell	His	Inquiry
Zebrafish	GATA5-8834Z	Recombinant Zebrafish GATA5	Mammalian Cell	His	Inquiry
Mouse	Gata5-1567M	Recombinant Mouse Gata5 Protein, His-tagged	E.coli	N-His	Inquiry
Rat	Gata5-1568R	Recombinant Rat Gata5 Protein, His-tagged	E.coli	N-His	Inquiry
Mouse	GATA5-3484M	Recombinant Mouse GATA5 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	GATA5-5470HF	Recombinant Full Length Human GATA5 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry
Human	GATA5-4751H	Recombinant Human GATA5 Protein, GST-tagged	Wheat Germ	GST	Inquiry

Involved Pathway Protein Function Interacting Protein GATA5 Related Articles

GATA5 involved in several pathways and played different roles in them. We selected most pathways GATA5 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Factors involved in megakaryocyte development and platelet production	AKAP1; GATA1A; GATA1; HBB-Y; KIF2B; ITPK1; HBD; BA2; MAFG; EHD1
Hemostasis	EHD1; G6b; CABLES1; KIFAP3; RAPGEF3; DOK2; ANXA2; AKAP10; CLEC1B; CD177

GATA5 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA5 itself. We selected most functions GATA5 had, and list some proteins which have the same functions with GATA5. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PBX1B; HLFB; ZNF302; ADAR; MAFBB; HOXC13B; ZNF789; ZNF497; PBRM1; TERF1
RNA polymerase II regulatory region sequence-specific DNA binding	SOX13; ZMYND11; STAT4; ZSCAN2; FOXD3; NFKB1; ARID5B; HMX1; ZGLP1; ZBTB4
RNA polymerase II transcription factor binding	GATA3; SPI1; HCLS1; ID4; KDM1A; GATA5; SPOP; CHST13; GATA1; DHX9
chromatin binding	TBL1Y; MKRN1; CEBPB; NSD1; KDM1A; BAZ1B; EGFR; FOSL2; ARID5A; OVOL2
enhancer sequence-specific DNA binding	ISL1; MYT1; GATA1; XBP1; TWIST1B; SOX9; FOXN4; GATA3; LDB1; KLF6A
metal ion binding	PDE3A; ZFP668; KLF12A; RPS6KAL; ZNF23; CYP2AD2; TRIM35-39; ZBED6; ZFPM1; ARSI
protein binding	RIPK2; YY1AP1; KLC3; NDUFS7; FMR1; AKAP12; CDX4; TINAGL1; MYOZ2; BAP1
sequence-specific DNA binding	NFIL3-4; HOXB5A; ISX; ZNF192; SOX21B; TCF7L2; Ar; FOXB1A; HDAC2; PRRX2
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	PKNOX1; CREB1; PTH; NFATC1; SPI1; RFX3; BHLHE40; RELA; SNAI2; HNF1B
transcription factor activity, sequence-specific DNA binding	ZBTB48; SOX1; NCOR1; ZNF624; ZNF613; ZIC5; MYNN; RUNX3; DMRT1; STAT1B
transcription regulatory region DNA binding	ARID5B; XBP1; BASP1; GLIS2; SMAD4; HINFP; TRP53; MTERFD3; CREB3L2; MLL1
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	OVOL2; SOX17; GATA1; ONECUT3; AIRE; MAFB; PKNOX1; GATA2; ATF1; PAX9
zinc ion binding	NR6A1A; RABGEF1; MMP25; MMP1A; GATAD2AB; MT2; EHMT2; TRIM55; PTGR1; CA4

GATA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA5.

Zhang, XL; Dai, N; et al. GATA5 loss-of-function mutation in familial dilated cardiomyopathy. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 35:763-770(2015).

Wang, J; Mao, JH; et al. A Novel NKX2.6 Mutation Associated with Congenital Ventricular Septal Defect. PEDIATRIC CARDIOLOGY 36:646-656(2015).

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