|Official Full Name||GATA binding protein 5|
|Background||The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.|
|Synonyms||GATA5; GATA binding protein 5; transcription factor GATA-5; bB379O24.1; GATA-binding factor 5; GATA5_HUMAN; GATA binding factor-5; GATA-binding protein 5|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GATA5 involved in several pathways and played different roles in them. We selected most pathways GATA5 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Factors involved in megakaryocyte development and platelet production||DOCK6; VPS45; IRF2; LRRC16A; DOCK11; MAFGB; DOCK10; DOCK8; GATA1A; KIF26A|
|Hemostasis||PROCA; CEACAM1; KIF5A; SERPINF2B; DOCK9; KIFAP3; GATA1A; GATA1; KIF3B; AKAP1|
GATA5 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA5 itself. We selected most functions GATA5 had, and list some proteins which have the same functions with GATA5. You can find most of the proteins on our site.
|DNA binding||DLX1A; DRAP1; PHTF1; ZBTB6; SNAPC4; HOXC9A; TOX; ERCC6L; ZNF823; ZNF23|
|RNA polymerase II regulatory region sequence-specific DNA binding||STAT4; SP3; EGR1; ZNF583; DLX2; BARX2; NEUROD2; PLAGL1; PHOX2B; EAF2|
|RNA polymerase II transcription factor binding||ZFPM2A; GSC; Ar; TRPS1; KDM1A; ZGLP1; CREBBP; MEF2A; T; WWP2|
|chromatin binding||MED1; PHF13; EED; PHC1; CUX1; SP100; LOXL2; NFIA; HMGB3B; WHSC1|
|enhancer sequence-specific DNA binding||LDB1; LMO4; XBP1; GATA4; SOX11; FOXN4; MYT1; TWIST1B; GATA5; YY1|
|metal ion binding||ZFP598; ZMYND12; CNOT8; HAGHL; MCCC1; LIMCH1A; GUCY1B3; CA5; CYP4A10; NR5A5|
|protein binding||SSSCA1; PEX1; TDRD7; FGFR1B; VAMP8; VSNL1; AP2M1; PHF20L1; TMEM149; NDRG4|
|sequence-specific DNA binding||FOXN3; ATF7; FOXO1A; TP53; HOXB6A; DLX1A; FOXO3; HOXB1B; FOXD4L1; RXRGB|
|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding||NKX2-1; POU3F3; SRF; SOX9; USF2; PROX1; SFPI1; FOXC2; RELA; SOX10|
|transcription factor activity, sequence-specific DNA binding||TBX16; IKZF3; FOXP4; ZFP35; MSC; ATOH1; Trl; RORA; TP63; AHR|
|transcription regulatory region DNA binding||REST; TFEB; TAF7L; POU5F1; TBX21; HDAC1; SOX2; KCNA3; CTCFL; TBL1X|
|transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding||FOXO3; BARHL1A; TBX5; IRF2; CSRNP3; MAFK; BHLHA15; ONECUT3; MAF; ATF3|
|zinc ion binding||RNF169; WBP4; TOPORS; MMP20; SOD1; NR2E3; XRN2; RBBP6; LHX2B; LHX1A|
GATA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA5.