GATA5 Protein

GATA5

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GATA5

Official Full Name GATA binding protein 5
Background The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.
Synonyms GATA5; GATA binding protein 5; transcription factor GATA-5; bB379O24.1; GATA-binding factor 5; GATA5_HUMAN; GATA binding factor-5; GATA-binding protein 5
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GATA5-4751H Recombinant Human GATA5 Protein, GST-tagged Wheat Germ GST
    Mouse GATA5-6226M Recombinant Mouse GATA5 Protein Mammalian Cell His
    Chicken GATA5-6972C Recombinant Chicken GATA5 Mammalian Cell His
    Zebrafish GATA5-8834Z Recombinant Zebrafish GATA5 Mammalian Cell His

    GATA5 involved in several pathways and played different roles in them. We selected most pathways GATA5 participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Factors involved in megakaryocyte development and platelet production DOCK6; VPS45; IRF2; LRRC16A; DOCK11; MAFGB; DOCK10; DOCK8; GATA1A; KIF26A
    Hemostasis PROCA; CEACAM1; KIF5A; SERPINF2B; DOCK9; KIFAP3; GATA1A; GATA1; KIF3B; AKAP1

    GATA5 has several biochemical functions, for example, DNA binding, RNA polymerase II regulatory region sequence-specific DNA binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GATA5 itself. We selected most functions GATA5 had, and list some proteins which have the same functions with GATA5. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding DLX1A; DRAP1; PHTF1; ZBTB6; SNAPC4; HOXC9A; TOX; ERCC6L; ZNF823; ZNF23
    RNA polymerase II regulatory region sequence-specific DNA binding STAT4; SP3; EGR1; ZNF583; DLX2; BARX2; NEUROD2; PLAGL1; PHOX2B; EAF2
    RNA polymerase II transcription factor binding ZFPM2A; GSC; Ar; TRPS1; KDM1A; ZGLP1; CREBBP; MEF2A; T; WWP2
    chromatin binding MED1; PHF13; EED; PHC1; CUX1; SP100; LOXL2; NFIA; HMGB3B; WHSC1
    enhancer sequence-specific DNA binding LDB1; LMO4; XBP1; GATA4; SOX11; FOXN4; MYT1; TWIST1B; GATA5; YY1
    metal ion binding ZFP598; ZMYND12; CNOT8; HAGHL; MCCC1; LIMCH1A; GUCY1B3; CA5; CYP4A10; NR5A5
    protein binding SSSCA1; PEX1; TDRD7; FGFR1B; VAMP8; VSNL1; AP2M1; PHF20L1; TMEM149; NDRG4
    sequence-specific DNA binding FOXN3; ATF7; FOXO1A; TP53; HOXB6A; DLX1A; FOXO3; HOXB1B; FOXD4L1; RXRGB
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding NKX2-1; POU3F3; SRF; SOX9; USF2; PROX1; SFPI1; FOXC2; RELA; SOX10
    transcription factor activity, sequence-specific DNA binding TBX16; IKZF3; FOXP4; ZFP35; MSC; ATOH1; Trl; RORA; TP63; AHR
    transcription regulatory region DNA binding REST; TFEB; TAF7L; POU5F1; TBX21; HDAC1; SOX2; KCNA3; CTCFL; TBL1X
    transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding FOXO3; BARHL1A; TBX5; IRF2; CSRNP3; MAFK; BHLHA15; ONECUT3; MAF; ATF3
    zinc ion binding RNF169; WBP4; TOPORS; MMP20; SOD1; NR2E3; XRN2; RBBP6; LHX2B; LHX1A

    GATA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GATA5.

    Zhang, XL; Dai, N; et al. GATA5 loss-of-function mutation in familial dilated cardiomyopathy. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 35:763-770(2015).
    Wang, J; Mao, JH; et al. A Novel NKX2.6 Mutation Associated with Congenital Ventricular Septal Defect. PEDIATRIC CARDIOLOGY 36:646-656(2015).

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