GNAL

  • Official Full Name

    guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

  • Synonyms

    GNAL;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type;guanine nucleotide-binding protein G(olf) subunit alpha;Adenylate cyclase stimulating G alpha protein, olfactory type;Guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type;Guanine nucleotide binding protein G(olf) subunit alpha;adenylate cyclase-stimulating G alpha protein, olfactory type;guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory typ

Recombinant Proteins

  • Zebrafish
  • Chicken
  • Human
  • Mouse
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • His
  • GST
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GNAL-1728Z Recombinant Zebrafish GNAL Mammalian Cells Zebrafish His
GNAL-1870C Recombinant Chicken GNAL Mammalian Cells Chicken His
GNAL-45H Recombinant Human GNAL protein, GST-tagged Wheat Germ Human GST 1-458 a.a.
GNAL-46H Recombinant Human GNAL protein, GST-tagged Wheat Germ Human GST 359-458 a.a.
GNAL-7017M Recombinant Mouse GNAL Protein Mammalian Cells Mouse His
GNAL-3759M Recombinant Mouse GNAL Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
GNAL-3759M-B Recombinant Mouse GNAL Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    GNAL involved in several pathways and played different roles in them. We selected most pathways GNAL participated on our site, such as Calcium signaling pathway,Dopaminergic synapse,Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Parkinsons disease GNAI3,UBE1Y1,NDUFS6,NDUFAB1,UBE2J1,NDUFB8,NDUFA8,NDUFB6,GPR37,NDUFC2
    Amoebiasis SERPINB1A,LAMC2,HSPB1,PIK3R1,ITGAM,SERPINB2,SERPINB3C,COL5A1,SERPINB6,PRKACB
    Calcium signaling pathway PHKA1,CHRM2,ADORA2AB,ORAI1,AGTR1B,P2RX3B,PRKACBB,CALM2,ORAI1B,GRIN1
    Dopaminergic synapse GRIN2A,PPP2R1B,DRD2,KCNJ6,KCNJ3,GNG10,PPP1CA,GNG11,DRD1A,GNG13
    Chagas disease (American trypanosomiasis) CCL2,MAPK1,MAPK9,TLR6,PPP2CA,SERPINE1,GNAI1,CD3E; CD3D,TGFBR1,MAPK3
    Olfactory transduction CNGA4,PDE2A,OR4N4,OR1A2,OR56A1,CALM4,OLFR186,OLFR486,OR10W1,OLFR474

    Protein Function

    GNAL has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding,G-protein coupled receptor binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAL itself. We selected most functions GNAL had, and list some proteins which have the same functions with GNAL. You can find most of the proteins on our site.

    Function Related Protein
    G-protein beta/gamma-subunit complex binding GNA13A,GNAT1,GNA15.4,GNAT2,GNAQ,CETN4,CETN1,GNA15.1,GNA12A,CETN2
    signal transducer activity TRIM54,VALOPB,FPR-RS3,LPAR2A,VMN1R44,GHRHRL,GPR186,TAAR14G,GPR132,MRGPRB1
    GTPase activity TUBG1,RAN,GTPBP2,RAB22A,GBP6,RAB2A,EEF1A1A,RAB5AB,RND2,DNM1A
    metal ion binding TP63,RNF150,RIOK2,ZSCAN10,HDAC8,PPM1BB,NR1D4A,ZNF543,NPTXR,MGAT4A
    GTP binding SUCLG1,SEPT8B,RAB18,GMPPB,RAB39A,ARF3A,RAB33A,GIMAP7,MXG,SRPRB
    G-protein coupled receptor binding RSPO2,HSPA1B,GNAI2,POMC,GNA11B,STUB1,PSAP,GNAI2A,GNA13A,FCN1

    Interacting Protein

    GNAL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAL here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAL.

    Haus1;BABAM1;SPATA2;USP3;15-deoxy-delta(12,14

    Resources

    References

    • Ziegan, J; Wittstock, M; et al. Novel GNAL Mutations in Two German Patients With Sporadic Dystonia. MOVEMENT DISORDERS 29:1833-1834(2014).
    • Dauer, W; et al. Inherited Isolated Dystonia: Clinical Genetics and Gene Function. NEUROTHERAPEUTICS 11:807-816(2014).

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