GNB1
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Official Full Name
Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 1 -
Overview
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. -
Synonyms
Gβ-1-Subunit;GNB1;Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;Guanine nucleotide binding protein (G protein), beta polypeptide 1;guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1;Beta subunit signal transducing proteins GS/GI;G protein beta 1 subunit;GBB1;Guanine nucleotide binding protein beta 1 subunit;Transducin beta chain 1;OTTHUMP00000001107;G protein, beta-1 subunit
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Flag
- Non
- Avi
- Fc
Involved Pathway
GNB1 involved in several pathways and played different roles in them. We selected most pathways GNB1 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Taste transduction | PRKACA,TAS2R42,TAS2R124,PLCB2,TAS2R104,TAS1R1,TAS2R113,TAS2R109,TAS2R38,GNAT3 |
| Retrograde endocannabinoid signaling | GABRD,GABRB3,SLC17A7,MAPK10,GNAQ,GNG13,GABRA1,GABRR3,GRIA3,GABRG1 |
| Ras signaling pathway | FOXO4,GNG12,ARF6,FGF11,INSR,PIK3CB,FGF8,IGF1R,BAD,PAK6 |
| Dopaminergic synapse | DRD5,GSK3B,GNAI3,CAMK2D,GNG2,ARNTL,GRIA1,KIF5A,MAPK12,AKT2 |
| GABAergic synapse | SLC12A5,GPHN,PRKACG,GNB3,GNG5,GABARAPL2,GNG12,GABARAPL1,Adcy4,GABRR2 |
| Cholinergic synapse | PRKCA,GNG8,MAPK1,CHRNA7,GNG13,PLCB1,CHRNB4,KCNJ4,GNAO1,Adcy4 |
| Serotonergic synapse | HTR3B,HTR1B,CYP2C39,CYP2D26,ALOX15B,BRAF,PRKACA,TPH1,PRKCB,MAPK1 |
| PIK-Akt signaling pathway | ITGA2B,PPP2R5A,GNG13,CRTC2,PPP2R2C,COL27A1,MDM2,THBS1,PIK3R1,ITGA1 |
| Glutamatergic synapse | GNG2,GNG5,PPP3CB,PRKACB,SLC38A3,GRIA2,GNG10,HOMER1,GLUL,PLA2G4A |
Protein Function
GNB1 has several biochemical functions, for example, GTPase activity,GTPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNB1 itself. We selected most functions GNB1 had, and list some proteins which have the same functions with GNB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | UNC13A,FCGR1A,DPP3,SCG2,PTPN11A,ASB6,NR2C2AP,PPP3R2,SOX1,CDK11B |
| signal transducer activity | GNA13B,ZDHHC13,CC2D1A,RGS6,NPY8BR,HTR5AL,GPR15,GNAL,UNC13B,GPR184 |
| GTPase activity | GBP3,RAB5C,GSPT2,RAB11AL,RAB1BA,TUFM,EIF2S3Y,GEM,EEF1A1A,SAR1B |
| type 1 angiotensin receptor binding | GNA13A,TYK2,JAK2,GNG3,AGT,GNA13,ARRB2,GNA13B,ARAP1,BDKRB2 |
| protein complex binding | PDX1,ABI1,CDK5RAP2,KLHL8,HCLS1,DAG1,WASF1,PTCH1,SIX2,KCTD5 |
| spectrin binding | UNC13A,DYNC1I1,MYO7A,ANK1,ADD2,EPB49,DCTN2,GBP1,PDE6G,SLC26A5 |
| GTPase binding | EPRS,VPS41,ENO1,GOLGA4,MARCH5,AIMP1,GM5506,STOML2,RAB3D,PTPRN |
Interacting Protein
GNB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNB1.
GNGT1;a8k1f4_human;GNAI2;Cdk1;NCF2;MCC;STIP1;MLF1;Cep76;PSMD2;q53fc7_human;Trim69;Haus1;NUDCD3;q96be0_human;PFDN5;MAP3K3;AARSD1;Mau2
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