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Official Full Name G protein-coupled receptor 4
Background G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.
Synonyms GPR4; G protein-coupled receptor 4; G-protein coupled receptor 4; G-protein coupled receptor 19
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GPR4-13476H Recombinant Human GPR4, GST-tagged E.coli GST
    Human GPR4-5242H Recombinant Human GPR4 Protein Wheat Germ N/A
    Human GPR4-5243H Recombinant Human GPR4 Protein, GST-tagged Wheat Germ GST
    Mouse GPR4-7188M Recombinant Mouse GPR4 Protein Mammalian Cell His
    Rat GPR4-2667R Recombinant Rat GPR4 Protein Mammalian Cell His
    Kit-1316 GPR4 CHO-K1 β-Arrestin Orphan GPCR Assay Kit N/A

    gpr4 involved in several pathways and played different roles in them. We selected most pathways gpr4 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with gpr4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class A/1 (Rhodopsin-like receptors) AGT; HCRT; RLN2; ADRa1A; GPR132B; DRD5; XK; EDNRAB; ADRB3; GPR17
    G alpha (q) signalling events OPN4B; MGLL; TRPC6A; KISS1; FFAR3; NPFF; NPS; FPR-RS6; LTB4R; RGS21
    GPCR downstream signaling ECT2; TRPC3; ADM2A; RGS21; OPN4B; ADORA1; CNR1; CCR3; AGT; DRD5
    GPCR ligand binding TAS2R3; RCA2.1; GPR17; CD97; TRH; ADM; ADM2A; EDNRB; CCR1; GPR55
    GPCRs, Class A Rhodopsin-like CMKLR1; CNR1; GPR63; CX3CR1; GPR31; GPR1; GPR12; NPFFR2; GPR75; OPN3
    Gastrin-CREB signalling pathway via PKC and MAPK PROKR2; OXTRL; GPR65; NPFF; GCGA; TRPC7; NPSR1; TAE1; UTS2; ANXA1
    Signal Transduction NCKIPSD; WNT8-2; CD97; WLS; SHARPIN; GRAP; RDH14; FGD4A; PYYA; OR56A1
    Signaling by GPCR NMBB; CD97; GPBAR1; ARHGEF25; PYY; EMR2; CCBP2; RGS10; TAS2R3; ARHGEF3

    gpr4 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by gpr4 itself. We selected most functions gpr4 had, and list some proteins which have the same functions with gpr4. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity PTGIR; ADRA2DA; MRGPRA5; OR2L5; MRGPRF; OXTRL; SMO; GPR183A; TMTOPS3A; VMN1R46

    gpr4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gpr4 here. Most of them are supplied by our site. Hope this information will be useful for your research of gpr4.

    Mochimaru, Y; Azuma, M; et al. Extracellular acidification activates ovarian cancer G-protein-coupled receptor 1 and GPR4 homologs of zebra fish. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 457:493-499(2015).
    Lu, ZY; Gui, HB; et al. Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 308:R283-R293(2015).

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