• Official Full Name

    glutathione peroxidase 2 (gastrointestinal)

  • Overview

    This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
  • Synonyms

    GPX2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase 2; GSHPX GI; Gastrointestinal glutathione peroxidase; GI GPx; Glutathione peroxidase gastrointestinal; Glutathione peroxidase related protein 2; Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPx 2; GPx-2; GPx-GI; GPX2_HUMAN; GSHPx 2; GSHPx-2; GSHPx-GI; gastrointestinal glutathione peroxidase 2; GI-GPx;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Baker's yeast
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPX2-29071TH Recombinant Human GPX2, His-tagged E.coli His
Human GPX2-1325H Recombinant Human Gutathione Proxidase 2 (gastrointestinal), His-tagged E.coli His
Human GPX2-5762HCL Recombinant Human GPX2 293 Cell Lysate HEK293 N/A
Human GPX2-13H Recombinant Human GPX2 Protein Tag Free
Human GPX2-5309H Recombinant Human GPX2 Protein, His-tagged E.coli His
Mouse GPX2-7231M Recombinant Mouse GPX2 Protein Mammalian Cell His
Mouse GPX2-3902M-B Recombinant Mouse GPX2 Protein Pre-coupled Magnetic Beads HEK293
Mouse GPX2-3902M Recombinant Mouse GPX2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Baker's yeast GPX2-1170B Recombinant Baker's yeast GPX2 protein, His&Myc-tagged E.coli His&Myc
Baker's yeast GPX2-1164B Recombinant Baker's yeast GPX2 protein, His-tagged E.coli His
Chicken GPX2-5203C Recombinant Chicken GPX2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPX2 Related Articles
  • GPX2 Related Research Area

GPX2 involved in several pathways and played different roles in them. We selected most pathways GPX2 participated on our site, such as Glutathione metabolism, Arachidonic acid metabolism, Thyroid hormone synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutathione metabolismGPX1A;GSTM;MGST2;MGST3;GSTP2;GSTM4;GSTA4;GSTM3;GSTM1
Arachidonic acid metabolismALOX5B.2;PTGDS;PTGR1;PTGESL;PLA2G2A;PLA2G12A;ALOX15B;CYP2P7;ALOX5A
Thyroid hormone synthesisTSHR;ASGR2;CANX;PRKCB;GPX1;PLCB3;LRP2;SLC5A5;GPX2

GPX2 has several biochemical functions, for example, electron carrier activity, glutathione peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPX2 itself. We selected most functions GPX2 had, and list some proteins which have the same functions with GPX2. You can find most of the proteins on our site.

Function Related Protein
electron carrier activityCYP1A2;NCF1;FDX1B;CYBA;TXNRD1;GSR;ACADM;GCDHB;UGDH
glutathione peroxidase activityGPX3;GPX6;GPX4A;PRDX6;GPX1;MGST3;GPX7;MGST2;GPX2

GPX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPX2.


van den Berg, L; Koelsch, BU; et al. Genetic dissection of the Mss4 locus mediating sex-biased cancer resistance in the rat peripheral nervous system. INTERNATIONAL JOURNAL OF CANCER 136:2099-2108(2015).
Bajak, E; Fabbri, M; et al. Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles. TOXICOLOGY LETTERS 233:187-199(2015).
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