GRIN3A

  • Official Full Name

    glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

  • Overview

    This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of;glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous;system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout;mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by;modulating NMDA receptor activity.

  • Synonyms

    GRIN3A;glutamate receptor, ionotropic, N-methyl-D-aspartate 3A;glutamate [NMDA] receptor subunit 3A;GluN3A;NMDAR3A;N-methyl-D-aspartate receptor subtype 3A;NR3A;NMDAR-L;FLJ45414

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GRIN3A-13536H Recombinant Human GRIN3A, His-tagged E.coli Human His 976-1081a.a.
GRIN3A-2704R Recombinant Rat GRIN3A Protein Mammalian Cells Rat His
GRIN3A-805H Recombinant Human GRIN3A Mammalian Cells Human His
GRIN3A-2358R Recombinant Rat GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GRIN3A-2358R-B Recombinant Rat GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Rat
GRIN3A-2364H Recombinant Human GRIN3A Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
GRIN3A-3079H Recombinant Human GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GRIN3A-3079H-B Recombinant Human GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Human
Grin3a-3309M Recombinant Mouse Grin3a Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    GRIN3A involved in several pathways and played different roles in them. We selected most pathways GRIN3A participated on our site, such as Alcoholism,Cocaine addiction,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction AGTR1B,DRD4A,RXFP2A,GH1,DRD1A,TAAR8B,GHR,CHRNA10,ADCYAP1R1A,HRH4
    Alcoholism HIST1H2AN,GNB5,PPP1CB,GM14483,GM14476,HIST1H4E,GNGT2,HIST1H2BK,HIST2H3C1,HIST1H2AF
    Cocaine addiction CREB3L2,GNAI2,CREB5,SLC18A2,GNAI3,GNAS,DRD1A,PRKACB,GRIA2,DLG4
    Glutamatergic synapse GRIN2B,GNGT2,GRIN2C,GRM8,SLC1A1,HOMER3,PLA2G4A,SLC17A8,GNAS,GNG13
    Nicotine addiction GABRA2,GABRG1,GABRR3,GABRA5,GABRQ,GRIA2,GABRA4,GRIN3B,GABRE,GABRB1
    cAMP signaling pathway CAMK2G,CALML5,GLP1R,GRIA1,PDE4D,CNGA1,GNAS,PDE4B,PRKACA,FFAR2

    Protein Function

    GRIN3A has several biochemical functions, for example, NMDA glutamate receptor activity,contributes_to NMDA glutamate receptor activity,calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN3A itself. We selected most functions GRIN3A had, and list some proteins which have the same functions with GRIN3A. You can find most of the proteins on our site.

    Function Related Protein
    protein binding UBL7,CPSF3,F2R,COG1,ECM1,HMGB3,TERT,HSPB2,EIF3J,CTSG
    protein phosphatase 2A binding ENSAA,SPHK1,MASTL,PPP2R4,SHC1,STRN4,AKT1,BCL2,HMGCR,EIF4EBP1
    contributes_to NMDA glutamate receptor activity GRIN2A,GRIN1,PTK2B
    glycine binding SIX2A,GSS,GRIN1,GLRA4A,GLRA2,GNMT,ALAS2,GLRA4B,SRR,GRIN2B
    extracellular-glutamate-gated ion channel activity GRIK1,GRIN1A,GRIK5,GRIA2,GRIN2BB,GRIK3,GRIN3B,GRIN2B,GRIN2A,GRIK4
    calcium channel activity TRPV6,TRPC7B,TRPN1,AKR1C1,TRPC1,TRPV4,CACNA1SA,CACNA1C,CACNA2D3,ITPR3
    NMDA glutamate receptor activity GRIN2A,GRIN1A,GRIN2D,GRIN2BB,GRIN3B,GRIN2B,GRIN1B,GRIN2C
    identical protein binding DES,PTK6,THG1L,AGXT2,RPE,GLUD1,CEACAM16,MIEF1,RYR2,IFIT3

    Interacting Protein

    GRIN3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN3A.

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