GRIN3A

  • Official Full Name

    glutamate receptor, ionotropic, N-methyl-D-aspartate 3A

  • Overview

    This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptors, which belong to the superfamily of;glutamate-regulated ion channels, and function in physiological and pathological processes in the central nervous;system. This subunit shows greater than 90% identity to the corresponding subunit in rat. Studies in the knockout;mouse deficient in this subunit suggest that this gene may be involved in the development of synaptic elements by;modulating NMDA receptor activity.

  • Synonyms

    GRIN3A;glutamate receptor, ionotropic, N-methyl-D-aspartate 3A;glutamate [NMDA] receptor subunit 3A;GluN3A;NMDAR3A;N-methyl-D-aspartate receptor subtype 3A;NR3A;NMDAR-L;FLJ45414

Recombinant Proteins

  • Human
  • Rat
  • Mouse
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Avi
  • Fc
  • DDK
  • Myc
Cat.# Product name Source (Host) Species Tag Protein Length Price
GRIN3A-13536H Recombinant Human GRIN3A protein, His-tagged E.coli Human His
GRIN3A-2704R Recombinant Rat GRIN3A Protein Mammalian Cells Rat His
GRIN3A-805H Recombinant Human GRIN3A Mammalian Cells Human His
GRIN3A-2358R Recombinant Rat GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
GRIN3A-2358R-B Recombinant Rat GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Rat
GRIN3A-2364H Recombinant Human GRIN3A Protein, MYC/DDK-tagged HEK293 Human DDK&Myc
GRIN3A-3079H Recombinant Human GRIN3A Protein, His (Fc)-Avi-tagged HEK293 Human Avi&Fc&His
GRIN3A-3079H-B Recombinant Human GRIN3A Protein Pre-coupled Magnetic Beads HEK293 Human
Grin3a-3309M Recombinant Mouse Grin3a Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc

    Involved Pathway

    GRIN3A involved in several pathways and played different roles in them. We selected most pathways GRIN3A participated on our site, such as Alcoholism,Cocaine addiction,Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIN3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction GABRP,PRLHR,SCTR,PTGER4A,CHRNA5,GPR50,TAAR12C,P2RX3A,GRM6B,PRSS1
    cAMP signaling pathway ATP2B4,RAC2,OXTR,GLP1R,CAMK2B,LOC100328615,PDE3B,ATP1A1,HTR1B,GRIN1
    Nicotine addiction SLC17A7,CHRNA6,GABRR3,GABRA3,GABRQ,SLC17A6,GABRG1,GABRB2,GABRG3,GABRR1
    Glutamatergic synapse Adcy4,GNG8,PRKCG,GLUL,GRM1,HOMER2,SLC1A1,TRPC1,GRM6,PLA2G4D
    Alcoholism GNG5,CRH,HIST1H2BN,H2AFB3,H2AFZ,HIST1H2BF,NTRK2,HIST1H2BE,HIST1H2BM,H2BFWT
    Cocaine addiction ATF6B,GNAI3,CREB3,ATF4,GRM2,NFKB1,CREB3L1,CREB3L2,GRIN2C,MAOB

    Protein Function

    GRIN3A has several biochemical functions, for example, NMDA glutamate receptor activity,contributes_to NMDA glutamate receptor activity,calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIN3A itself. We selected most functions GRIN3A had, and list some proteins which have the same functions with GRIN3A. You can find most of the proteins on our site.

    Function Related Protein
    NMDA glutamate receptor activity GRIN2BB,GRIN1B,GRIN2D,GRIN1A,GRIN2C,GRIN2B,GRIN3B,GRIN2A
    glycine binding GLRA1,GRIN1,GRIN3B,GSS,GLDC,SRR,GRIN2B,GLRA2,GLRA4B,GNMT
    calcium channel activity RYR1B,RYR1,PKD1,TRPC3,CACNA1C,TRPC4B,TRPV2,CACNG2A,TRPV1,AKR1C1
    protein phosphatase 2A binding SMG7,BCL2,ENSA,STRN,IGBP1,CPD,EIF4EBP1,PPP2R2A,SHC1,STRN4
    protein binding CENPH,P2RY1,Ccl27a,PDCL3,APOA2,TSEN54,RICTOR,ARHGEF40,SMR3B,AATF
    extracellular-glutamate-gated ion channel activity GRID2,GRIA1B,GRIN2D,GRIA3,GRIA4B,GRIA2B,KBP,GRIN2C,GRIK3,GRIA1A
    identical protein binding IMPA1,DNM1,LRRK2,TRADD,MPST,COL18A1,NELL2,DIAPH1,SYP,SDCBP
    contributes_to NMDA glutamate receptor activity GRIN1,PTK2B,GRIN2A

    Interacting Protein

    GRIN3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIN3A here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIN3A.

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