grip1 Protein, glutamate receptor interacting protein 1


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Official Full Name glutamate receptor interacting protein 1
Background This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms GRIP1; glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP-1; AMPA receptor-interacting protein GRIP1
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GRIP1-12H Recombinant Human GRIP1 Protein, GST-tagged Wheat Germ GST
    Human GRIP1-1747H Recombinant Human GRIP1 protein, His & T7-tagged E.coli His/T7
    Human GRIP1-5741HCL Recombinant Human GRIP1 293 Cell Lysate HEK293 N/A
    Mouse GRIP1-7277M Recombinant Mouse GRIP1 Protein Mammalian Cell His
    Rat GRIP1-2707R Recombinant Rat GRIP1 Protein Mammalian Cell His
    Zebrafish GRIP1-3973Z Recombinant Zebrafish GRIP1 Mammalian Cell His

    grip1 involved in several pathways and played different roles in them. We selected most pathways grip1 participated on our site, such as BDNF signaling pathway, Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with grip1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    BDNF signaling pathway CSNK2A1P; LINGO1; EIF4E; FRS3; BCL2L11; MAP3K2; CDK5; DOK5; SIRPA; CDKL5
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity CACNG2; MYO6; AKAP5; NSFB; NSFA; PICK1; CACNG3; HAND2; GRIP1
    Neuronal System KCNAB3; CHRNA5; KCNK18; SYN2; CACNB4B; LIN7C; KCNF1A; KCNMB1; KCNC3A; KCNK16
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell HAND2; PICK1; DLG1L; MYO6; CAMKK1B; CHRNE; GRIP1; CHRNA2; NSFA; CHRNA5
    Trafficking of AMPA receptors PICK1; HAND2; GRIP1
    Trafficking of GluR2-containing AMPA receptors PICK1; HAND2; GRIP1
    Transmission across Chemical Synapses GABRR2A; SLC18A3A; SNAP25B; CAMKK1B; SYT1A; PICK1; SLC1A2B; PPFIA2; PPFIA4; SYN1

    grip1 has several biochemical functions, for example, androgen receptor binding, beta-catenin binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by grip1 itself. We selected most functions grip1 had, and list some proteins which have the same functions with grip1. You can find most of the proteins on our site.

    Function Related Protein
    androgen receptor binding DAXX; EP300; PIAS1; FOXH1; NCOA1; FHL2; RNF4; CCNE1; CDK7; KDM1A
    beta-catenin binding CDH2; MED12; PTPRU; GSK3B; ESR1; KLF4; PSEN1; TCF7L1B; DACT2; TRPC4
    glucocorticoid receptor binding ETS2; GRIP1; CEBPB; NR4A2; EP300; NRIP1; STAT3; STAT5B; FKBP4; YWHAH
    protein C-terminus binding HOMER3; VTA1; XRCC4; CACNA1B; CAV3; EP300; PEX12; TOP2A; PPP1R9B; ITGB3BP
    protein binding RECQL; MAPK1; NUP133; TBXAS1; STUB1; ABCD2; TRIM41; RNF20; SLN; CARHSP1
    receptor signaling complex scaffold activity CARD10; MAGI2; GRIP2A; GRIP1; NCK1; G3BP2; MMS19; SPAG9A; CD3G; CD3E
    transcription coactivator activity NFKB2; SCAND1; NCOA2; TAF1; STIL; FHL2; KDM5A; NPM1; YY1; TAF9

    grip1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with grip1 here. Most of them are supplied by our site. Hope this information will be useful for your research of grip1.


    Dobroyolna, J; Chinenov, Y; et al. Glucocorticoid-Dependent Phosphorylation of the Transcriptional Coregulator GRIP1. MOLECULAR AND CELLULAR BIOLOGY 32:730-739(2012).
    Selak, S; Paternain, AV; et al. A Role for SNAP25 in Internalization of Kainate Receptors and Synaptic Plasticity. NEURON 63:357-371(2009).

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