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Official Full Name GTF2I repeat domain containing 1
Background The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
Synonyms GTF2IRD1; GTF2I repeat domain containing 1; GTF2I repeat domain containing 1 , WBSCR11; general transcription factor II-I repeat domain-containing protein 1; BEN; binding factor for early enhancer; Cream1; GTF3; MusTRD1; RBAP2; WBSCR12; General transcription factor II I repeat domain containing protein 1; General transcription factor III; GTF2I repeat domain containing protein 1; Muscle TFII I repeat domain-containing protein 1; MusTRD1/BEN; Slow muscle fiber enhancer binding protein; USE B1 binding protein; WBSCR11; Williams Beuren syndrome chromosome region 11 protein; OTTHUMP00000160822; OTTHUMP00000213171; OTTHUMP00000213172; OTTHUMP00000213173; USE B1-binding protein; general transcription factor 3; binding factor for earl; WBS; hMusTRD1alpha1
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GTF2IRD1-13602H Recombinant Human GTF2IRD1, His-tagged E.coli His
    Human GTF2IRD1-1638H Recombinant Human GTF2IRD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GTF2IRD1-1663H Recombinant Human GTF2IRD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GTF2IRD1-4457H Recombinant Human GTF2IRD1 Protein, GST-tagged Wheat Germ GST
    Human GTF2IRD1-5691HCL Recombinant Human GTF2IRD1 293 Cell Lysate HEK293 N/A
    Human GTF2IRD1-5692HCL Recombinant Human GTF2IRD1 293 Cell Lysate HEK293 N/A
    Mouse Gtf2ird1-3328M Recombinant Mouse Gtf2ird1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse GTF2IRD1-7364M Recombinant Mouse GTF2IRD1 Protein Mammalian Cell His
    Rhesus Macaque GTF2IRD1-2011R Recombinant Rhesus monkey GTF2IRD1 Protein, His-tagged Mammalian Cell His

    gtf2ird1 involved in several pathways and played different roles in them. We selected most pathways gtf2ird1 participated on our site, such as Basal transcription factors, cGMP-PKG signaling pathway, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with gtf2ird1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal transcription factors TAF15; GTF2H2C; TAF2; GTF2H1; TAF5; GTF2E1; TBPL1; GTF2IRD1; TAF12; TAF1L
    cGMP-PKG signaling pathway IRS1; PPP3CB; CALM1; GTF2IRD1; ATP1A2; PIK3R1; PPP1R12A; NFATC1; ATP1A4; PLCB1
    Herpes simplex infection TYK2; IFNPHI3; IFNA13; C3; CLOCKA; NFKB1; SRPK1A; SRPK1; TAF6L; Casp3

    gtf2ird1 has several biochemical functions, for example, DNA binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gtf2ird1 itself. We selected most functions gtf2ird1 had, and list some proteins which have the same functions with gtf2ird1. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding RBPJ; TBX5B; ASH2L; LBX1; NKX2.2B; NR1D4B; ZBTB43; SP140; NR4A2B; ZNF554
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding OLIG2; CIR1; GATA4; GATA5; MEF2A; SOX9; GLI1; TFAP4; ZFHX3; NKX2
    transcription factor activity, sequence-specific DNA binding ZSCAN12; AFF4; ZNF16; HOXA4A; EOMES; DBPA; ELK3; HOXB8; CEBPB; SOX11B

    gtf2ird1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gtf2ird1 here. Most of them are supplied by our site. Hope this information will be useful for your research of gtf2ird1.

    ABL1; EXOSC4

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