Recombinant Human GTF2IRD1 Protein, GST-tagged

• Cat.No.: GTF2IRD1-4457H
• Product Overview: Human GTF2IRD1 full-length ORF ( AAH18136, 1 a.a. - 959 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 131.01 kDa
• AA Sequence: MALLGKRCDVPTNGCGPDRWNSAFT RKDEIITSLVSALDSMCSALSKLNA EVACVAVHDESAFVVSTEKGRMFLN ARKELQSDFLRFCRGPPWKDPEAEH PKKVQRGEGGGRSLPRSSLEHGSDV YLLRKMVEEVFDVLYSEALGRASVV PLPYERLLREPGLLAVQGLPEGLAF RRPAEYDPKALMAILEHSHRIRFKL KRPLEDGGRDSKALVELNGVSLIPK GSRDCGLHGQAPKVPPQDLPPTATS SSMASFLYSTALPNHAIRELKQEAP SCPLAPSDLGLSRPMPEPKATGAQD FSDCCGQKPTGPGGPLIQNVHASKR ILFSIVHDKSEKWDAFIKETEDINT LRECVQILFNSRYAEALGLDHMVPV PYRKIACDPEAVEIVGIPDKIPFKR PCTYGVPKLKRILEERHSIHFIIKR MFDERIFTGNKFTKDTTKLEPASPP EDTSAEVSRATVLDLAGNARSDKGS MSEDCGPGTSGELGGLRPIKIEPED LDIIQVTVPDPSPTSEEMTDSMPGH LPSEDSGYGMEMLTDKGLSEDARPE ERPVEDSHGDVIRPLRKQVELLFNT RYAKAIGISEPVKVPYSKFLMHPEE LFVVGLPEGISLRRPNCFGIAKLRK ILEASNSIQFVIKRPELLTEGVKEP IVDSQGTASSLGFSPPALPPERDSG DPLVDESLKRQGFQENYDARLSRID IANTLREQVQDLFNKKYGEALGIKY PVQVPYKRIKSNPGSVIIEGLPPGI PFRKPCTFGSQNLERILAVADKIKF TVTRPFQGLIPKPDEDDANRLGEKV ILREQVKELFNEKYGEALGLNRPVL VPYKLIRDSPDAVEVTGLPDDIPFR NPNTYDIHRLEKILKAREHVRMVII NQLQPFAEICNDAKVPAKDSSIPKR KRKRVSEGNSVSSSSSSSSSSSSNP DSVASANQISFVQWPMYMVDYAGLN VQLPGPLNY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GTF2IRD1 GTF2I repeat domain containing 1 [ Homo sapiens ]
• Official Symbol: GTF2IRD1
• Synonyms: GTF2IRD1; GTF2I repeat domain containing 1; GTF2I repeat domain containing 1 , WBSCR11; general transcription factor II-I repeat domain-containing protein 1; BEN; binding factor for early enhancer; Cream1; GTF3; MusTRD1; RBAP2; WBSCR12; USE B1-binding protein; general transcription factor 3; general transcription factor III; slow-muscle-fiber enhancer-binding protein; Williams-Beuren syndrome chromosome region 11; williams-Beuren syndrome chromosomal region 12 protein; muscle TFII-I repeat domain-containing protein 1 alpha 1; WBS; CREAM1; MUSTRD1; WBSCR11; hMusTRD1alpha1
• Gene ID: 9569
• mRNA Refseq: NM_001199207
• Protein Refseq: NP_001186136
• MIM: 604318
• UniProt ID: Q9UHL9