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HCK

  • Official Full Name

    hemopoietic cell kinase

  • Overview

    Hck is a member of the Src family of non-receptor tyrosine kinases involved in the modulation of a wide variety of normal and pathogenic cellular processes including growth, development, differentiation, and carcinogenesis. These proteins contain a consen
  • Synonyms

    HCK; hemopoietic cell kinase; tyrosine-protein kinase HCK; JTK9; p59-HCK/p60-HCK; hematopoietic cell kinase; p59Hck; p61Hck;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • His|T7
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HCK-1412H Active Recombinant Human HCK, GST-tagged Sf9 Insect Cell GST 230-497 aa
Human HCK-97H Activated Recombinant Human HCK(230-497) Protein, N-His-tagged Sf21 His 230-497 aa
Human HCK-98H Active Recombinant Human HCK(230-497) Protein, N-His-tagged Sf21 His 230-497 aa
Human HCK-327H Recombinant Human Hemopoietic Cell Kinase, GST-tagged, Active Sf9 Insect Cell GST
Human HCK-29189TH Recombinant Human HCK, GST-tagged E.coli GST
Human HCK-7854H Recombinant Human HCK protein, His & T7-tagged E.coli His/T7 Gly2~Pro526 (Accession # P08631)
Human HCK-1235H Recombinant Human Hemopoietic Cell Kinase, His-tagged Insect Cell His
Human HCK-171H Recombinant Human Hemopoietic Cell Kinase, SH3 Domain, GST-tagged E.coli GST
Human HCK-4625H Active Recombinant Human HCK Protein, GST-His-tagged Insect Cell GST/His
Human HCK-4626H Recombinant Human HCK Protein, GST-tagged Wheat Germ GST
Human HCK-774HCL Recombinant Human HCK cell lysate N/A
Human HCK-1057H Recombinant Human HCK Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HCK-0757H Recombinant Human HCK Protein (I81-P526), Tag Free Insect Cell No tag I81-P526
Human HCK-3511HF Recombinant Full Length Human HCK Protein, GST-tagged In Vitro Cell Free System GST 505 amino acids
Human HCK-0758H Recombinant Human HCK Protein (I81-P526), His tagged Insect Cell His I81-P526
Human HCK-2845H Recombinant Human HCK Protein (Met22-Pro526), N-His tagged E.coli N-His Met22-Pro526
Mouse Hck-7855M Recombinant Mouse Hck protein, His & T7-tagged E.coli His/T7 Gly2~Pro524 (Accession # P08103)
Mouse Hck-1100M Recombinant Mouse Hck Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat HCK-2805R Recombinant Rat HCK Protein Mammalian Cell His
Rat HCK-2460R-B Recombinant Rat HCK Protein Pre-coupled Magnetic Beads HEK293
Rat HCK-2460R Recombinant Rat HCK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Kit-1599 HCK Kinase Binding Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HCK Related Articles
  • HCK Related Research Area

HCK involved in several pathways and played different roles in them. We selected most pathways HCK participated on our site, such as Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chemokine signaling pathwayGNB2;RAP1A;RELA;RAC2;GNAI2;GNG4;CCR7;NFKBIB;CCL21
Fc gamma R-mediated phagocytosisNCF1;PIK3CB;ASAP2;PIP5K1C;MARCKSL1;PRKCE;SPHK2;WASF2;ASAP1

HCK has several biochemical functions, for example, ATP binding, non-membrane spanning protein tyrosine kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HCK itself. We selected most functions HCK had, and list some proteins which have the same functions with HCK. You can find most of the proteins on our site.

Function Related Protein
ATP bindingPRKD1;PANK1;CAMK2D1;CFTR;KIF5C;PRKCE;MAP4K4;UBE2K;TTLL5
non-membrane spanning protein tyrosine kinase activityJAK2A;PRKCD;WEE2;TEC;YRK;JAK3;FYNA;PTK2BB;PTK2B
protein bindingBBS7;RIBC1;MAB21L1;HCK;RAD23B;TTC19;PI4KA;TRIM44;GPM6A
protein tyrosine kinase activityBCR;MAP3K9;ERBB4A;MAP3K11;JAK3;EPHA4B;DSTYK;CSF1RA;NTRK3A
receptor bindingPVRL3;CNPY4;MIF;PVR;HLA-E;Itga10&Itgb1;SLC9A3R2;TNFSF10;PTK2AA

HCK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCK here. Most of them are supplied by our site. Hope this information will be useful for your research of HCK.

KHDRBS1; polg_hcvh; WAS; SOS1

Stegeman, H; Kaanders, JHAM; et al. Combining radiotherapy with MEK1/2, STAT5 or STAT6 inhibition reduces survival of head and neck cancer lines. MOLECULAR CANCER 12:-(2013).
Ben-Zimra, M; Bachelet, I; et al. Eosinophil major basic protein activates human cord blood mast cells primed with fibroblast membranes by integrin-beta 1. ALLERGY 68:1259-1268(2013).
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