herpud1

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herpud1

Official Full Name homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
Background The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
Synonyms HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; SUP; HERP; Mif1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; MMS-inducible; methyl methanesulfonate (MMF)-inducible fragment protein 1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein;
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HERPUD1-1378H Recombinant Human HERPUD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HERPUD1-4695H Recombinant Human HERPUD1 Protein, GST-tagged Wheat Germ GST
    Human HERPUD1-5439H Recombinant Human HERPUD1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human HERPUD1-5584HCL Recombinant Human HERPUD1 293 Cell Lysate HEK293 N/A
    Human HERPUD1-5585HCL Recombinant Human HERPUD1 293 Cell Lysate HEK293 N/A
    Human HERPUD1-628H Recombinant Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, His-tagged E.coli His
    Zebrafish HERPUD1-3151Z Recombinant Zebrafish HERPUD1 Mammalian Cell His

    herpud1 involved in several pathways and played different roles in them. We selected most pathways herpud1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with herpud1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Protein processing in endoplasmic reticulum HSPA8; FBXO2; SEC62; DNAJC5G; DNAJB1B; RPN2; LMAN1L; UBE2J2; CALR; EDEM3

    herpud1 has several biochemical functions, for example, ion channel binding, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by herpud1 itself. We selected most functions herpud1 had, and list some proteins which have the same functions with herpud1. You can find most of the proteins on our site.

    Function Related Protein
    ion channel binding KCNB1; CAV1; TRPC1; KCNE2; LYN; DLG1; FXYD1; CIB1; DIAPH1; EPN1
    molecular_function UBTD1A; FIP1L1B; MARCH9; HHLA1; CX34.4; HGH1; TMEM239; EMC6; GHDC; ANKRD52A
    protein binding AP1B1; BLOC1S2; RMI1; MICA; DCLRE1B; RASSF2; AARSD1; RING1; HIST2H3C; ZFYVE1

    herpud1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with herpud1 here. Most of them are supplied by our site. Hope this information will be useful for your research of herpud1.

    UBXN6; IMPA2; XRCC6; RPA2; CD58; ARHGDIA; EWSR1; USP7; TOLLIP; STARD9

    Prantner, AM; Turini, M; et al. Anti-Mesothelin Nanobodies for Both Conventional and Nanoparticle-Based Biomedical Applications. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 11:1201-1212(2015).
    Huang, XL; Xu, ZD; et al. Gold nanoparticle-based dynamic light scattering immunoassay for ultrasensitive detection of Listeria monocytogenes in lettuces. BIOSENSORS & BIOELECTRONICS 66:184-190(2015).

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