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Official Full Name histone cluster 1, H1c
Background Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two;molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp;of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between;nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and;encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a;palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Synonyms HIST1H1C; histone cluster 1, H1c; H1 histone family, member 2 , H1F2, histone 1, H1c; histone H1.2; H1.2; H1 histone family member 2; H1.a; H12_HUMAN; H1F2; Histone 1 H1c; Histone cluster 1 H1c; Histone H1d; MGC3992; histone 1, H1c; H1 histone family, member 2; H1C
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HIST1H1C-2088H Recombinant Human Histone Cluster 1 E.coli N/A
    Human HIST1H1C-210H Recombinant Human HIST1H1C, GST-tagged Wheat Germ GST
    Human HIST1H1C-259H Recombinant Human HIST1H1C Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human HIST1H1C-5553HCL Recombinant Human HIST1H1C 293 Cell Lysate HEK293 N/A
    Mouse HIST1H1C-7644M Recombinant Mouse HIST1H1C Protein Mammalian Cell His

    hist1h1c involved in several pathways and played different roles in them. We selected most pathways hist1h1c participated on our site, such as Activation of DNA fragmentation factor, Apoptosis, Apoptosis induced DNA fragmentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist1h1c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of DNA fragmentation factor HIST1H1A; HIST1H1C; HMGB2A; HMGB2; HIST1H1B; HIST1H1D; HIST1H1E; DFFA; H1F0
    Apoptosis induced DNA fragmentation HMGB2A; HMGB2; HIST1H1B; H1F0; HIST1H1A; HIST1H1C; DFFA; HIST1H1D; HIST1H1E
    Apoptotic execution phase PKP1; CTNNB1; STK24A; DNM1L; STK24B; BMX; ADD1; CTNNB2; OCLN; STK26
    Cellular Senescence Txn1; H3F3D; SCMH1; HIST4H4; ASF1A; HTATIP; RBBP7; RBBP4; BMI1B; CDK6
    Cellular responses to stress GABARAP; NUP50; SUZ12A; HIST1H1D; DPF1; KAT5; DYNLL2A; HSBP1; H3F3D; EED
    DNA Damage/Telomere Stress Induced Senescence HMGA1B; HIST1H1C; ASF1A; EP400; HIST1H1D; HIST1H1A; UBN1; ACD; CABIN1; TERF2
    Formation of Senescence-Associated Heterochromatin Foci (SAHF) ASF1A; CABIN1; HMGA1-RS1; HIRA; UBN1; HMGA1B; HIST1H1B; H1F0; HIST1H1D; HIST1H1A

    hist1h1c has several biochemical functions, for example, chromatin DNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hist1h1c itself. We selected most functions hist1h1c had, and list some proteins which have the same functions with hist1h1c. You can find most of the proteins on our site.

    Function Related Protein
    chromatin DNA binding BCL6; SMAD3; SRF; INSM1B; EP300; APEX1; MYOD1; RELA; VAX2; RUVBL2
    poly(A) RNA binding FBL; RPLP0; RPS9; ERH; DDX28; ELAC2; COA6; HNRNPM; RPL32; MCAT
    protein binding KLHL12; STAG3; KCNQ4; UPF1; CHID1; HIST1H4F; MCCC2; WDR25; C22orf39; RPL39L

    hist1h1c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist1h1c here. Most of them are supplied by our site. Hope this information will be useful for your research of hist1h1c.

    YBX1; TOP1; RELA; F10; CSNK2A2; ssrna_ag

    Wang, ZF; Sirotkin, AM; et al. The mouse histone H1 genes: Gene organization and differential regulation. JOURNAL OF MOLECULAR BIOLOGY 271:124-138(1997).

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