|Official Full Name||histone cluster 1, H3a|
|Background||Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]|
|Synonyms||HIST1H3A; histone cluster 1, H3a; H3/A; H3FA; histone H3.1; histone H3/a; histone 1, H3a; H3 histone family, member A;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
hist1h3a involved in several pathways and played different roles in them. We selected most pathways hist1h3a participated on our site, such as Alcoholism, Transcriptional misregulation in cancer, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist1h3a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Alcoholism||HDAC4; HIST2H3A; NPY; HDAC5; BRAF; HIST1H2BD; FOSB; H2AFZ; HIST3H3; BDNF|
|Transcriptional misregulation in cancer||FLT3; HIST2H3A; IL3; HIST1H3H; MLL1; DEFA3; SPINT1; WHSC1; SLC45A3; FCGR1|
|Systemic lupus erythematosus||TRIM21; SSB; ACTN4; HIST1H2BA; HIST1H4I; HIST1H4A; ACTN3; HIST2H2AC; GRIN2B; HIST1H2BO|
hist1h3a has several biochemical functions, for example, DNA binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hist1h3a itself. We selected most functions hist1h3a had, and list some proteins which have the same functions with hist1h3a. You can find most of the proteins on our site.
|DNA binding||GTF2E2; ZFP521; ZBTB12; ZNF497; PCBP2; DEK; ZBTB43; NR2F6A; TOMM20A; TCEB3C|
|histone binding||HIST1H4F; NCL; L3MBTL1; H3F3A; CTSL2; HIST1H3A; RCC1; NAP1L2; HIST2H3C1; HJURP|
|protein binding||BECN1; FGD5; NOMO2; SWAP70; CNOT8; SLC4A1; SYT6; ICAM1; DTL; ZKSCAN4|
|protein heterodimerization activity||HIST1H4A; SNX1; BOKB; RRAGD; TAL1; HIST1H4J; SMAD4; UGT1A4; UGT1A7; SYT5|
hist1h3a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist1h3a here. Most of them are supplied by our site. Hope this information will be useful for your research of hist1h3a.
CBX1; CBX5; WDR5