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Official Full Name histone cluster 2, H3c
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Synonyms H3; H3.2; H3/M; H3F2; H3FM; H3FN; histone cluster 2, H3c; HIST2H3C
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HIST2H3C-114H Recombinant Human HIST2H3C Protein, HIS-tagged E.coli HIS
    Human HIST2H3C-4813H Recombinant Human HIST2H3C Protein, GST-tagged Wheat Germ GST
    Human HIST2H3C-5515HCL Recombinant Human HIST2H3C 293 Cell Lysate HEK293 N/A
    Zebrafish HIST2H3C-5890Z Recombinant Zebrafish HIST2H3C Mammalian Cell His

    hist2h3c involved in several pathways and played different roles in them. We selected most pathways hist2h3c participated on our site, such as Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Alcoholism, Amyloid formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hist2h3c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 HIST2H3C; KDM4C; HIST4H4; KDM1A; HIST3H2BB; NCOA2
    Amyloid formation LTF; CALCA; ODAM; SAA1; MFGE8; NAT8; NAT8B; APCS; HIST3H2BB; TGFBI
    Cell Cycle CLIP1; RCC2; BARD1; ORC3; SKP1; SKA2; SKP2; GORASP1; CEP57; TINF2
    Cell Cycle, Mitotic E2F3; CDK5RAP2; ENSAA; ZW10; NIPBL; DPF1; STAG2; CDCA5; CDKN2C; PHF8
    Cellular Senescence CDKN2B; HTATIP; Txn1; E2F3; HMGA1-RS1; UBN1; TNIK; TERF2IP; HIST1H1A; PHC2
    Cellular responses to stress PRDX3; KIAA1967; AMBRA1B; DYNLL2B; CBX8; CDK6; MAPKAPK2B; WDR45L; ULK1A; POT1
    Chromatin modifying enzymes TADA2B; KDM5C; KDM2A; KDM4C; PBRM1; SUZ12; MCRS1; KAT8; EP400; CAPNS2

    hist2h3c has several biochemical functions, for example, DNA binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hist2h3c itself. We selected most functions hist2h3c had, and list some proteins which have the same functions with hist2h3c. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding HIST1H2BC; NKX2.2B; ZFP507; ZNF2; EGR2B; ZNF554; SOX6; DDX20; LHX2A; ELF2A
    histone binding NCL; HIST1H3H; CTSL2; HIST1H4A; HIST1H3G; BRD7; HAT1; APBB1; HIST1H3A; CTCFL
    protein binding DNAJB11; PARVG; CRH; PEA15; NR2F6; NSMCE1; KLF17; CLIC2; LEPROT; AAAS
    protein heterodimerization activity BAXB; CD3G; LTC4S; Fzd4; GABPB1; HIST1H2BP; HIST1H2BA; ATF4; CHRNA5; CHUK

    hist2h3c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hist2h3c here. Most of them are supplied by our site. Hope this information will be useful for your research of hist2h3c.

    Ywhae; Ywhaz

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