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HKDC1

Official Full Name

hexokinase domain containing 1
Synonyms

HKDC1;hexokinase domain containing 1;FLJ22761;FLJ37767;Q2TB90;MGC125688;OTTHUMP00000019718;putative hexokinase HKDC1;Hexokinase domain-containing protein 1;EC 2.7.1;EC 2.7.1.1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	HKDC1-315H	Recombinant Human HKDC1 Protein, MYC/DDK-tagged	HEK293	Myc/DDK	Inquiry
Human	HKDC1-4828H	Recombinant Human HKDC1 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	HKDC1-795HCL	Recombinant Human HKDC1 cell lysate		N/A	Inquiry
Human	HKDC1-1345H	Recombinant Human HKDC1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	HKDC1-7715M	Recombinant Mouse HKDC1 Protein	Mammalian Cell	His	Inquiry
Mouse	HKDC1-4230M-B	Recombinant Mouse HKDC1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	Hkdc1-3408M	Recombinant Mouse Hkdc1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Mouse	HKDC1-4230M	Recombinant Mouse HKDC1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	HKDC1-6544Z	Recombinant Zebrafish HKDC1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
HKDC1 Related Articles

HKDC1 involved in several pathways and played different roles in them. We selected most pathways HKDC1 participated on our site, such as Glycolysis / Gluconeogenesis, Fructose and mannose metabolism, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HKDC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycolysis / Gluconeogenesis	ALDOAB;G6PCA.1;LDHBB;ALDH3B2;PGM1;BPGM;ADH4;HK3;TPI1
Fructose and mannose metabolism	ALDOC;HK2;PFKFB2;PFKP;GMPPB;TIGARB;PFKMB;PFKFB1;GMPPAA
Galactose metabolism	G6PCA.1;AKR1B8;Akr1b3;HKDC1;B4GALT1;PFKMA;PFKMB;GANC;GALM
Starch and sucrose metabolism	UXS1;AMY2A4;GYS2;UGP2A;AMY2A2;UGT2A1;UGT1A6B;HKDC1;UGT2A3
Amino sugar and nucleotide sugar metabolism	RENBP;GKUP;GALT;GPR19;PMM1;PGM2;NANS;GFPT2;CMASA
Butirosin and neomycin biosynthesis	HK3;HK2;HK1;HKDC1
Metabolic pathways	MVK;AKR1A1B;MTMR1B;POLR3C;PLCB4;DGKD;EHHADH;RDH11;DPYD
Carbon metabolism	MDH2;TKT;GPR19;GOT2;PSPH;PKMA;DLD;PGAM2;ALDOAA
HIF- signaling pathway	AKT1;PIK3R3;TFRC;EIF4E1B;PDHB;NOX3;PDK1;MAPK3;ARNT
Insulin signaling pathway	MAP2K1;RAPGEF1;CBLC;BRAF;PDPK1B;CALM2;PRKACB;SHC2;MAPK8A
Type II diabetes mellitus	PIK3R5;SLC2A2;PRKCZ;INSR;ADIPOQ;PIK3CG;IRS1;MAFA;INS
Carbohydrate digestion and absorption	G6PC;PIK3CD;G6PC3;PIK3R2;GNAT3;AMY1B;HKDC1;ATP1A2;SLC37A4
Central carbon metabolism in cancer	MAPK3;PFKM;PDHA2;G6PDX;GLS2;MAPK1;GLS;PGAM1;MET

HKDC1 has several biochemical functions, for example, ATP binding, fructokinase activity, glucokinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HKDC1 itself. We selected most functions HKDC1 had, and list some proteins which have the same functions with HKDC1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	SWAP70;JAK2B;VWA8;AURKB;CCT8L2;ADCY7;CAMK2D1;PAPOLB;ATP2B1B
fructokinase activity	HK1;HKDC1;HK3;HK2
glucokinase activity	HK2;HK3;HK1;HKDC1
glucose binding	HK2;HKDC1;UGP2;G6PDX;HK1;G6PD;GYS1;PYGL;SLC2A3
mannokinase activity	HK2;HK3;HK1;HKDC1

HKDC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HKDC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HKDC1.

ssrna_ug

Hu, CJ; Song, G; et al. Identification of New Autoantigens for Primary Biliary Cirrhosis Using Human Proteome Microarrays. MOLECULAR & CELLULAR PROTEOMICS 11:669-680(2012).

Hashimoto, M; Wilson, JE; et al. Kinetic and regulatory properties of HKI+, a modified form of the type I isozyme of mammalian hexokinase in which interactions between the N- and C-terminal halves have been disrupted. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 399:109-115(2002).