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Official Full Name major histocompatibility complex, class II, DQ beta 1
Background HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1, later, it was among 3 types DQw1 (later DQ1, and split into DQ5 and DQ6), DQw2 and DQw3. Of these three serotyping specificities only DQw1 recognized DQ alpha chain. The serotype is positive in individuals who bear the DQA1*01 alleles. The most frequently found within this group are: DQA1*0101, *0102, *0103, and *0104. In the illustration on the right, DQ1 serotyping antibodies recognizes the DQ alpha (magenta), where antibodies to DQA1* gene products bind variable regions close to the peptide binding pocket.
Synonyms CELIAC1; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA DQB; HLA DQB1; IDDM1; Lymphocyte antigen; Major histocompatibility complex class II beta; Major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA DQ beta 1; MHC class II DQ beta chain; MHC class II HLA DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; OTTHUMP00000029167; OTTHUMP00000178569; OTTHUMP00000178570; OTTHUMP00000178571; HLA-DQB1; DQw1
    • Species :
    • Human
    • Source :
    • HEK293
    • Wheat Germ
    • Tag :
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HLA-DQB1-12H Recombinant Human HLA-DQB1 protein, GST-tagged Wheat Germ GST
    Human HLA-DQB1-27714TH Recombinant Human HLA-DQB1 Wheat Germ N/A
    Human HLA-DQB1-5496HCL Recombinant Human HLA 293 Cell Lysate HEK293 N/A
    Human HLA-DQB1-802H Recombinant Human HLA-DQB1 protein, GST-tagged Wheat Germ GST

    hla-dqb1 involved in several pathways and played different roles in them. We selected most pathways hla-dqb1 participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with hla-dqb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome ITGB1; ATP6AP1; ATP6V0E1; ITGB3B; FCGR2C; H2-Q10; TFRC; NOX1; CD36; NOS1
    Cell adhesion molecules (CAMs) NRXN3A; CDH3; CD86; CLDN20; NEO1A; CLDNG; MHC2DEB; HLA-DOB; ITGAL; ITGAV
    Antigen processing and presentation PSME2; H2-AB1; HLA-B; KLRC3; CTSL1; HLA-DMB; Ctsl; HSP90AB1; KIR2DL1; HLA-DMA
    Intestinal i IL-15RA; IL5; BLB1; ITGB7; ITGA4; IL4; AICDA; CXCL12; HLA-DRB4; HLA-DRB1
    ne network for IgA production CD86; CD28; HLA-DQB1; MHC2A; HLA-DRB1; TGFB1; H2-AA; MHC2DCB; ITGB7; HLA-DRB5
    Type I diabetes mellitus INS2; HLA-DRB3; H2-AA; HLA-G; GZMB; HLA-DPB1; HLA-B; HLA-DRB4; PRF1; HLA-DRB1
    Leishmaniasis HLA-DRB3; IL1B; ITGB2; HLA-DMA; HLA-DQA1; ITGB1; PRKCB; MAP3K7; MAPK13; PTGS2
    Toxoplasmosis PDPK1; HLA-DPB1; PIK3CD; BIRC7; LAMA1; LAMA5; MAP2K3; PIK3R1; LDLR; TYK2
    Staphylococcus aureus infection DSG1C; HLA-DQB1; FCGR4; C1S; C5AR1; HLA-DOB; HLA-DRB1; CFH; FPR2; MBL2
    Tuberculosis RAF1; IRAK1; RAB5B; HLA-DRB5; LAMP2; CAMK2B; ATP6V1H; EP300; IFNA2; CD209A
    Influenza A IFNA2; Ifna15; TNFRSF10C; BLA; HSPA2; HLA-DRB4; IL12A; EIF2AK2; AKT2; NXF2
    HTLV-I infection HLA-DPB1; CDC27; WNT5A; LTA; HLA-DRA; ZFP36; WNT5B; FZD9; BCL2L1; ANAPC2
    Herpes simplex infection IL6; EIF2AK4; CCL2; IFIH1; MAPK8; MAPK9; USP7; TLR2-1; HCFC1; STAT1B
    Epstein-Barr virus infection PIK3R2; RAN; NFKBIB; HSPA1B; NFKBIA; MAP2K3; IFNG; PSMC3; CD40; HDAC5
    Asthma CCL11; FCER1G; CD40; HLA-DRA; H2-AB1; HLA-DMA; TNF; IL10; HLA-DOB; RNASE3
    Autoi TSHR; Ifna15; CD80; IFNA4; IFNA2; TSHB; FASLG; HLA-DQA2; CD28; CD40LG
    ne thyroid disease H2-AB1; HLA-DQB1; HLA-B; GZMB; HLA-DRB1; Ifna15; HLA-F; HLA-DRB3; HLA-DOB; HLA-C
    Inflammatory bowel disease (IBD) TLR5; TNF; IL4; RELA; HLA-DPA1; IL13; Il4ra; TBX21; Il23a; HLA-DMB
    Systemic lupus erythematosus HLA-DQB1; H2BFWT; H2-AB1; FCGR3; H2AFJ; HIST1H3D; FCGR2A; C8A; HIST1H2BK; HIST1H2BF
    Rheumatoid arthritis HLA-DPA1; CXCL5; TNFSF13; H2-AA; Ccl12; ATP6V0A2; HLA-DQB1; HLA-DPB1; IL-8; ANGPT1
    Allograft rejection HLA-DRB3; MICA; HLA-DQA2; HLA-DQB1; HLA-E; PRF1; CD28; HLA-DRB5; HLA-G; CD86
    Graft-versus-host disease HLA-DOB; KLRC1; KIR2DL1; HLA-DMA; H2-AA; HLA-DRB3; HLA-DRB5; HLA-DRB4; KIR2DL3; HLA-DMB
    Viral myocarditis CXADR; HLA-DRB4; CD28; HLA-E; SGCD; HLA-A; HLA-DRA; ITGB2L; HLA-DRB1; HLA-DRB5

    hla-dqb1 has several biochemical functions, for example, MHC class II receptor activity, peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hla-dqb1 itself. We selected most functions hla-dqb1 had, and list some proteins which have the same functions with hla-dqb1. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II receptor activity HLA-DRB1; HLA-DQA2; KRT17; HLA-DRB4; HLA-DRA; HLA-DQA1; HLA-DQB2; HLA-DPA1; HLA-DQB1; HLA-DOA
    peptide antigen binding MHC1ZBA; MHC1UKA; MHC1ZE; TAPBP; HLA-A; HLA-C; MHC1ZFA; H2-AB1; MHC1UXA2; HLA-DRB3

    hla-dqb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hla-dqb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of hla-dqb1.


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