HLA-DQB1 Protein

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HLA-DQB1

Official Full Name	major histocompatibility complex, class II, DQ beta 1
Background	HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1, later, it was among 3 types DQw1 (later DQ1, and split into DQ5 and DQ6), DQw2 and DQw3. Of these three serotyping specificities only DQw1 recognized DQ alpha chain. The serotype is positive in individuals who bear the DQA101 alleles. The most frequently found within this group are: DQA10101, 0102, 0103, and 0104. In the illustration on the right, DQ1 serotyping antibodies recognizes the DQ alpha (magenta), where antibodies to DQA1 gene products bind variable regions close to the peptide binding pocket.
Synonyms	CELIAC1; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA DQB; HLA DQB1; IDDM1; Lymphocyte antigen; Major histocompatibility complex class II beta; Major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA DQ beta 1; MHC class II DQ beta chain; MHC class II HLA DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; OTTHUMP00000029167; OTTHUMP00000178569; OTTHUMP00000178570; OTTHUMP00000178571; HLA-DQB1; DQw1;

Type:

Species :
Human

Source :
E.coli
HEK293
In Vitro Cell Free System
Wheat Germ

Tag :
GST
His
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	HLA-DQB1-12H	Recombinant Human HLA-DQB1 protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	HLA-DQB1-802H	Recombinant Human HLA-DQB1 protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	HLA-DQB1-27714TH	Recombinant Human HLA-DQB1	Wheat Germ	N/A	Inquiry
Human	HLA-DQB1-5496HCL	Recombinant Human HLA 293 Cell Lysate	HEK293	N/A	Inquiry
Human	HLA-DQB1-4097H	Recombinant Human HLA-DQB1 protein, His-tagged	E.coli	His	Inquiry
Human	HLA-DQB1-673HF	Recombinant Full Length Human HLA-DQB1 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry
Human	HLA-DQB1-683HF	Recombinant Full Length Human HLA-DQB1 Protein, GST-tagged	In Vitro Cell Free System	GST	Inquiry

Involved Pathway Protein Function Interacting Protein

HLA-DQB1 involved in several pathways and played different roles in them. We selected most pathways HLA-DQB1 participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HLA-DQB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Phagosome	THBS3A; NOS1; CD209C; MHC2A; THBS4B; Cd209g; VAMP3; RAB7A; MRC1; ATP6V1E2
Cell adhesion molecules (CAMs)	ITGB2L; PECAM1; TIGIT; CLDN1; Icosl; HLA-F; BLA; H2-Q10; HLA-DQB1; CDH5
Antigen processing and presentation	IFNG; HSPA1A; KLRC1; KIR3DL1; HSPA2; H2-AA; NFYA; TAP2; H2-AB1; Ctsl
Intestinal i	BMA1; MHC2A; CCL25B; BLB1; HLA-DMB; ICOSLG; BLB2; Il2; PIGR; BLA
ne network for IgA production	ICOS; BLB1; Il2; MADCAM1; HLA-DRB5; HLA-DRB4; TNFRSF13B; TGFB1A; HLA-DMA; TNFSF13
Type I diabetes mellitus	HLA-DQA2; GAD2; HLA-E; HLA-DOA; HLA-A; HLA-DMA; PTPRN2; HLA-DRB3; HLA-DQA1; IL12B
Leishmaniasis	IL12B; HLA-DRB4; FCGR3B; NFKBIB; MAPK12; IL12A; PRKCB; MAPK11; TGFB2; TGFB3
Toxoplasmosis	TRAF6; IRAK1; HLA-DQB1; HSPA8; HLA-DRA; LAMC2; MAPK10; HLA-DRB4; MAPK8; LAMB4
Staphylococcus aureus infection	CFB; FCGR3A; C2; FCGR2C; cgr2b; DSG1A; FPR1; FCGR2B; H2-AB1; FCGR3B
Tuberculosis	MAPK13; H2-AB1; TLR2; HLA-DRB3; ATP6V1H; MRC1; ATP6V0D2; ITGB2L; TLR4; HLA-DQA1
Influenza A	HLA-DRB4; H2-AA; MAPK11; HLA-DRB5; HLA-DRB3; GSK3B; LOC780933; IRF3; CASP1; OAS1
HTLV-I infection	HLA-DPA1; WNT8A; MYB; AKT1; POLD2; FZD2; TERT; CDC23; SLC25A6; HLA-F
Herpes simplex infection	IL1B; EIF2AK2; GLTSCR2; PML; IFN-a; EIF2AK3; IFNA2; PPP1CB; MCRS1; CCL2
Epstein-Barr virus infection	TYK2; FGR; SPI1; SFPI1; FCER2; PIK3CG; IRF3; HLA-DQA1; POLR2F; SNW1
Asthma	HLA-DOA; H2-AB1; HLA-DRB4; CCL11; IL5; HLA-DMB; IL9; HLA-DRB3; HLA-DMA; HLA-DQB1
Autoi	HLA-DPB1; FAS; HLA-DRA; IFNA1; HLA-DRB1; Ifna11; HLA-G; HLA-DMA; H2-AB1; HLA-DQA2
ne thyroid disease	IFNA8; IFNA16; HLA-DRB1; CD80; HLA-DOA; IFNA7; TPO; HLA-F; HLA-A; HLA-DQA2
Inflammatory bowel disease (IBD)	TBX21; Il23a; Il12b; HLA-DRB5; IL2RG; IL18; TLR4; RELA; STAT6; IL23R; IL17A
Systemic lupus erythematosus	HIST2H3C1; GM6026; ACTN3; TROVE2; HIST2H2BE; HIST1H4M; HIST1H4I; C1S; HLA-DRB1; C3
Rheumatoid arthritis	HLA-DRB5; HLA-DRB4; FOS; ATP6V1C2; ATP6V1H; H2-AB1; HLA-DQA1; TNFSF11; ATP6AP1; ICAM1
Allograft rejection	IL4; Fasl; HLA-DOB; TNF; HLA-G; HLA-DPA1; HLA-DMB; Il2; HLA-DRB5; CD80
Graft-versus-host disease	FAS; HLA-G; HLA-C; IFNG; KLRC1; HLA-DMA; HLA-E; HLA-DQA1; HLA-DPA1; CD80
Viral myocarditis	RAC1; PRF1; HLA-DOB; HLA-A; H2-AA; ABL1; HLA-C; H2-Q10; Casp3; HLA-DMA

HLA-DQB1 has several biochemical functions, for example, MHC class II receptor activity, peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLA-DQB1 itself. We selected most functions HLA-DQB1 had, and list some proteins which have the same functions with HLA-DQB1. You can find most of the proteins on our site.

Function	Related Protein
MHC class II receptor activity	HLA-DRB1; HLA-DRB3; HLA-DQA1; HLA-DOB; HLA-DRB4; HLA-DOA; KRT17; HLA-DQB1; HLA-DQA2; HLA-DQB2
peptide antigen binding	HLA-DRA; MHC1UEA; CLEC4M; HLA-DQB1; MAML1; TAPBP; HLA-DQA1; H2-AB1; TUBB3; HLA-G

HLA-DQB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLA-DQB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HLA-DQB1.

HLA-DQA1

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HLA-DQB1 Protein

HLA-DQB1

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HLA-DQB1

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