HLA-DQB1 Protein


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Official Full Name major histocompatibility complex, class II, DQ beta 1
Background HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1, later, it was among 3 types DQw1 (later DQ1, and split into DQ5 and DQ6), DQw2 and DQw3. Of these three serotyping specificities only DQw1 recognized DQ alpha chain. The serotype is positive in individuals who bear the DQA1*01 alleles. The most frequently found within this group are: DQA1*0101, *0102, *0103, and *0104. In the illustration on the right, DQ1 serotyping antibodies recognizes the DQ alpha (magenta), where antibodies to DQA1* gene products bind variable regions close to the peptide binding pocket.
Synonyms CELIAC1; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA DQB; HLA DQB1; IDDM1; Lymphocyte antigen; Major histocompatibility complex class II beta; Major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA DQ beta 1; MHC class II DQ beta chain; MHC class II HLA DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta; OTTHUMP00000029167; OTTHUMP00000178569; OTTHUMP00000178570; OTTHUMP00000178571; HLA-DQB1; DQw1;
    • Type:
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HLA-DQB1-12H Recombinant Human HLA-DQB1 protein, GST-tagged Wheat Germ GST Inquiry
    Human HLA-DQB1-802H Recombinant Human HLA-DQB1 protein, GST-tagged Wheat Germ GST Inquiry
    Human HLA-DQB1-27714TH Recombinant Human HLA-DQB1 Wheat Germ N/A Inquiry
    Human HLA-DQB1-5496HCL Recombinant Human HLA 293 Cell Lysate HEK293 N/A Inquiry
    Human HLA-DQB1-4097H Recombinant Human HLA-DQB1 protein, His-tagged E.coli His Inquiry
    Human HLA-DQB1-673HF Recombinant Full Length Human HLA-DQB1 Protein, GST-tagged In Vitro Cell Free System GST Inquiry
    Human HLA-DQB1-683HF Recombinant Full Length Human HLA-DQB1 Protein, GST-tagged In Vitro Cell Free System GST Inquiry

    HLA-DQB1 involved in several pathways and played different roles in them. We selected most pathways HLA-DQB1 participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HLA-DQB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome THBS3A; NOS1; CD209C; MHC2A; THBS4B; Cd209g; VAMP3; RAB7A; MRC1; ATP6V1E2
    Cell adhesion molecules (CAMs) ITGB2L; PECAM1; TIGIT; CLDN1; Icosl; HLA-F; BLA; H2-Q10; HLA-DQB1; CDH5
    Antigen processing and presentation IFNG; HSPA1A; KLRC1; KIR3DL1; HSPA2; H2-AA; NFYA; TAP2; H2-AB1; Ctsl
    Intestinal i BMA1; MHC2A; CCL25B; BLB1; HLA-DMB; ICOSLG; BLB2; Il2; PIGR; BLA
    ne network for IgA production ICOS; BLB1; Il2; MADCAM1; HLA-DRB5; HLA-DRB4; TNFRSF13B; TGFB1A; HLA-DMA; TNFSF13
    Type I diabetes mellitus HLA-DQA2; GAD2; HLA-E; HLA-DOA; HLA-A; HLA-DMA; PTPRN2; HLA-DRB3; HLA-DQA1; IL12B
    Leishmaniasis IL12B; HLA-DRB4; FCGR3B; NFKBIB; MAPK12; IL12A; PRKCB; MAPK11; TGFB2; TGFB3
    Toxoplasmosis TRAF6; IRAK1; HLA-DQB1; HSPA8; HLA-DRA; LAMC2; MAPK10; HLA-DRB4; MAPK8; LAMB4
    Staphylococcus aureus infection CFB; FCGR3A; C2; FCGR2C; cgr2b; DSG1A; FPR1; FCGR2B; H2-AB1; FCGR3B
    Tuberculosis MAPK13; H2-AB1; TLR2; HLA-DRB3; ATP6V1H; MRC1; ATP6V0D2; ITGB2L; TLR4; HLA-DQA1
    Influenza A HLA-DRB4; H2-AA; MAPK11; HLA-DRB5; HLA-DRB3; GSK3B; LOC780933; IRF3; CASP1; OAS1
    HTLV-I infection HLA-DPA1; WNT8A; MYB; AKT1; POLD2; FZD2; TERT; CDC23; SLC25A6; HLA-F
    Herpes simplex infection IL1B; EIF2AK2; GLTSCR2; PML; IFN-a; EIF2AK3; IFNA2; PPP1CB; MCRS1; CCL2
    Epstein-Barr virus infection TYK2; FGR; SPI1; SFPI1; FCER2; PIK3CG; IRF3; HLA-DQA1; POLR2F; SNW1
    ne thyroid disease IFNA8; IFNA16; HLA-DRB1; CD80; HLA-DOA; IFNA7; TPO; HLA-F; HLA-A; HLA-DQA2
    Inflammatory bowel disease (IBD) TBX21; Il23a; Il12b; HLA-DRB5; IL2RG; IL18; TLR4; RELA; STAT6; IL23R; IL17A
    Systemic lupus erythematosus HIST2H3C1; GM6026; ACTN3; TROVE2; HIST2H2BE; HIST1H4M; HIST1H4I; C1S; HLA-DRB1; C3
    Rheumatoid arthritis HLA-DRB5; HLA-DRB4; FOS; ATP6V1C2; ATP6V1H; H2-AB1; HLA-DQA1; TNFSF11; ATP6AP1; ICAM1
    Allograft rejection IL4; Fasl; HLA-DOB; TNF; HLA-G; HLA-DPA1; HLA-DMB; Il2; HLA-DRB5; CD80
    Graft-versus-host disease FAS; HLA-G; HLA-C; IFNG; KLRC1; HLA-DMA; HLA-E; HLA-DQA1; HLA-DPA1; CD80
    Viral myocarditis RAC1; PRF1; HLA-DOB; HLA-A; H2-AA; ABL1; HLA-C; H2-Q10; Casp3; HLA-DMA

    HLA-DQB1 has several biochemical functions, for example, MHC class II receptor activity, peptide antigen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLA-DQB1 itself. We selected most functions HLA-DQB1 had, and list some proteins which have the same functions with HLA-DQB1. You can find most of the proteins on our site.

    Function Related Protein
    MHC class II receptor activity HLA-DRB1; HLA-DRB3; HLA-DQA1; HLA-DOB; HLA-DRB4; HLA-DOA; KRT17; HLA-DQB1; HLA-DQA2; HLA-DQB2
    peptide antigen binding HLA-DRA; MHC1UEA; CLEC4M; HLA-DQB1; MAML1; TAPBP; HLA-DQA1; H2-AB1; TUBB3; HLA-G

    HLA-DQB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLA-DQB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HLA-DQB1.


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