|Official Full Name||homeobox A7|
|Background||In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.|
|Synonyms||HOXA7; homeobox A7; homeo box A7 , HOX1, HOX1A; homeobox protein Hox-A7; ANTP; Homeobox protein HOX 1A; Homeobox protein Hox A7; Homeotic protein antennapedia; Hox 1.1; HOX1; HOX1A; homeo box A7; OTTHUMP00000217256; homeobox protein HOX-1A; homeobox protein Hox 1.1; HOX1.1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
hoxa7 involved in several pathways and played different roles in them. We selected most pathways hoxa7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with hoxa7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
hoxa7 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, sequence-specific DNA binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hoxa7 itself. We selected most functions hoxa7 had, and list some proteins which have the same functions with hoxa7. You can find most of the proteins on our site.
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||TFE3; NR3C1; JUNBA; ARNT2; HELT; MYOD1; FOSL1A; ISL1; CEBPG; MITF|
|sequence-specific DNA binding||KLF2; NKX2.4B; NR1D4B; NR2F2; TEFB; DBX1; NR6A1A; ZFP42; GATA5; HOXC13B|
|transcription factor binding||JUND; SIRT1; PSMD4; CDK9; JUN; EPAS1; NFKBIA; SRF; TMEM173; LCOR|
|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding||HEYL; MEOX2; KLF5; Ar; FOXC2; CEBPA; ZIC1; TFE3B; EHF; FOXA1|
hoxa7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hoxa7 here. Most of them are supplied by our site. Hope this information will be useful for your research of hoxa7.
NPM1; JUNB; PEX5