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Official Full Name homeobox B5
Background This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Synonyms HOXB5; homeobox B5; homeo box B5 , HOX2, HOX2A; homeobox protein Hox-B5; HGNC:5116; HHO.C10; Homeo box 2A; Homeo box B5; Homeobox 2A; Homeobox protein HHO.C10; Homeobox protein Hox B5; Homeobox protein Hox-2A; Homeobox protein HoxB5; Homeobox protein Hu-1; Homeobox2A; HomeoboxB5; HOX 2; Hox 2.1; HOX 2A; HOX B5; HOX2; Hox2.1; HOX2A; HOXB 5; HU 1; HU1; HXB5_HUMAN; HU-1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HOXB5-1896H Recombinant Human HOXB5 Protein, His-tagged E.coli His
    Human HOXB5-28512TH Recombinant Human HOXB5 Wheat Germ N/A
    Human HOXB5-4962H Recombinant Human HOXB5 Protein, GST-tagged Wheat Germ GST
    Human HOXB5-5422HCL Recombinant Human HOXB5 293 Cell Lysate HEK293 N/A
    Cynomolgus Monkey HOXB5-593C Recombinant Cynomolgus HOXB5 Protein, His-tagged Mammalian Cell His
    Chicken HOXB5-2209C Recombinant Chicken HOXB5 Mammalian Cell His

    hoxb5 involved in several pathways and played different roles in them. We selected most pathways hoxb5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with hoxb5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    hoxb5 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding, protein binding, transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by hoxb5 itself. We selected most functions hoxb5 had, and list some proteins which have the same functions with hoxb5. You can find most of the proteins on our site.

    Function Related Protein
    RNA polymerase II distal enhancer sequence-specific DNA binding MSC; TFAP2C; NR5A2; POU4F1; H2AFZ; H3F3A; ZBTB16; PAX4; NR1H4; NFE2L1
    protein binding FAM71C; S1PR2; TNFAIP1; KIAA0408; RAB25; SCG2; ZNF502; BATF2; ARL4C; DSTN
    transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding MEOX2; BACH1; NFE2L2; ZEB2; ARID3B; SIX6; TARDBP; PROP1; NFATC1; SIX3

    hoxb5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hoxb5 here. Most of them are supplied by our site. Hope this information will be useful for your research of hoxb5.


    Fessner, A; Esser, JS; et al. The transcription factor HoxB5 stimulates vascular remodelling in a cytokine-dependent manner. CARDIOVASCULAR RESEARCH 101:247-255(2014).
    Volpe, MV; Ramadurai, SM; et al. Regulatory Interactions between Androgens, Hoxb5, and TGF beta Signaling in Murine Lung Development. BIOMED RESEARCH INTERNATIONAL :-(2013).

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