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HSPD1

  • Official Full Name

    heat shock 60kDa protein 1 (chaperonin)

  • Overview

    Heat Shock Protein 60 (HSP60) is a chaperonin with roles in mitochondrial protein import and folding of polypeptides in the mitochondrial matrix.
  • Synonyms

    HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60; chaperonin 60; 60 kDa chaperonin; heat shock protein 65;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Fc|His
  • GST
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSPD1-1555H Active Recombinant Human HSPD1 protein, His-tagged E.coli His
Human HSPD1-06H Recombinant Human Heat Shock 60kDa Protein 1 (Chaperonin) E.coli N/A
Human HSPD1-3896H Recombinant Human HSPD1, His tagged E.coli His
Human HSPD1-241H Recombinant Human HSPD1 protein, His-tagged E.coli His
Human HSPD1-8545H Recombinant Human HSPD1, His-GST tagged E.coli Fc/His
Human HSPD1-4854H Recombinant Human Heat Shock 60kDa Protein 1 (Chaperonin), GST-tagged E.coli GST
Human HSPD1-29396TH Recombinant Human HSPD1, His-tagged E.coli His
Human HSPD1-270H Recombinant Human HSPD1 protein, His/MBP-tagged E.coli His/MBP 305-426 aa
Human HSPD1-326H Recombinant Human Heat Shock 60kDa Protein 1 (Chaperonin), His-tagged; E.coli His
Human HSPD1-28422TH Recombinant Human HSPD1 E.coli N/A 573 amino acids
Human HSPD1-5340HCL Recombinant Human HSPD1 293 Cell Lysate HEK293 N/A
Human HSPD1-5652HF Recombinant Full Length Human HSPD1 Protein, GST-tagged In Vitro Cell Free System GST 573 amino acids
Human HSPD1-5264H Recombinant Human HSPD1 Protein, GST-tagged Wheat Germ GST
Human HSPD1-041H Recombinant Human HSPD1 Protein E.coli 573
Human HSPD1-022H Active Recombinant Human HSPD1 Protein, His-tagged E.coli His 2-573
Human HSPD1-3090H Recombinant Human HSPD1 Protein (Ala27-Phe573), N-His tagged E.coli N-His Ala27-Phe573
Human HSPD1-150H Recombinant Human HSPD1 Protein, His-tagged E. coli His 2-573
Mouse Hspd1-7778M Recombinant Mouse Hspd1 protein, His & T7-tagged E.coli His/T7 Met316~Phe573 (Accession # P63038)
Mouse Hspd1-4058M Recombinant Mouse Hspd1 protein, His-tagged E.coli His Leu2-Phe573
Mouse Hspd1-242M Recombinant Mouse Hspd1 protein, His-tagged E.coli His
Mouse HSPD1-7923M Recombinant Mouse HSPD1 Protein Mammalian Cell His
Mouse HSPD1-4369M Recombinant Mouse HSPD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSPD1-4369M-B Recombinant Mouse HSPD1 Protein Pre-coupled Magnetic Beads HEK293
Rat Hspd1-243R Recombinant Rat Hspd1 protein, His-tagged E.coli His
Rat HSPD1-2957R Recombinant Rat HSPD1 Protein Mammalian Cell His
Rat HSPD1-2612R-B Recombinant Rat HSPD1 Protein Pre-coupled Magnetic Beads HEK293
Rat HSPD1-2612R Recombinant Rat HSPD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSPD1-2171R Recombinant Rhesus monkey HSPD1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSPD1-1992R Recombinant Rhesus Macaque HSPD1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSPD1-1992R-B Recombinant Rhesus Macaque HSPD1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HSPD1-9616Z Recombinant Zebrafish HSPD1 Mammalian Cell His
Chicken HSPD1-2131C Recombinant Chicken HSPD1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSPD1 Related Articles

HSPD1 involved in several pathways and played different roles in them. We selected most pathways HSPD1 participated on our site, such as RNA degradation, Type I diabetes mellitus, Legionellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA degradationDnaK;CNOT7;PAN3;PABPC5;EXOSC8;EXOSC6;DDX6;LSM6;XRN2
Type I diabetes mellitusCD86;INS1;HLA-DMB;HLA-DRB3;GAD1;HLA-F;HLA-DPB1;HLA-E;IL12A
LegionellosisIL18;NAIP7;HSPA1B;HSPA2;IL-8;NAIP6;CD14;HSPA8;C3
TuberculosisTLR4;Cd209g;ITGAM;IL12B;SPHK2;RELA;TRAF6;HLA-DOA;FCGR3A

HSPD1 has several biochemical functions, for example, ATP binding, ATPase activity, DNA replication origin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPD1 itself. We selected most functions HSPD1 had, and list some proteins which have the same functions with HSPD1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingP2RX4A;MYH6;CLCN4-2;NUBP1;ACSF2;MAP2K2A;DGKZ;EARS2;ABCF2
ATPase activityKIF3C;CARNS1;HSPA8;ABCG2A;MYO19;ABCF3;ATF7IP;KIF4;KIF9
DNA replication origin bindingORC3L;MCM5;MCM2;ORC4L;MCM10;ORC2L;ORC4;HSPD1;CDC45
chaperone bindingBAG4;BAK1;DNAJA3A;ATP1A3;SLC25A17;BAX;ERP29;PFDN6;TRP53
double-stranded RNA bindingDHX58;DGCR8;AGO1;TUBB4B;MSN;STAU1;HMGB1;EIF2C3;TUBA1B
insulin bindingHSPD1;IDE;C2CD2L;IGF1R;PIK3R1;INSR
lipopolysaccharide bindingPTAFR;DROSHA;KIAA0644;SPON2;CD6;TLR4;SELP;BPI;TRIL
misfolded protein bindingHSPA5;F12;STUB1;SDF2L1;BAG6;HSPD1;HDAC6;CLU;EDEM1
p53 bindingEHMT2;EHMT1;CHD8;CREBBP;TP73;SETD8;ZNF385A;ZMAT4;SMARCA4
poly(A) RNA bindingNCL;RPS10;C11orf68;SRSF5;KPNB1;RPL7;MFAP1;ARL6IP4;RPL3
protease bindingADAM8A;POLG;Cstb;SERPINA5;CFLAR;Serpina1c;INS;SERPINA1D;TNFRSF10A
protein bindingCRLF1;FBXO18;SYCE1;AP1G2;IQSEC3;CSTF3;POLR1C;MGRN1;SLC22A7
protein complex bindingLRP1;AKAP5;RNF40;RIPK1;ADM2;ERCC6;SLC9A3R1;NCKAP1;TRADD
protein heterodimerization activityPOU5F3;ITGB1A;TAF6;NEUROD2;HIST3H2BB;TAS1R2;SPNA1;CHRNB2;HIST1H2B8
single-stranded DNA bindingRPA3;TREX1;RAD51AP1;RPA4;SSBP3;NABP1A;TTC6;MCM6;TSNAX
ubiquitin protein ligase bindingMAGEA2;BAG4;CUL4B;TRAF5;CUL3A;PRKAR2A;AICDA;UBE2G1;PINK1
unfolded protein bindingPPIA;H2-KE2;CRYABA;HSPA1A;ERLEC1;ST13;AIPL1;PFDN6;CLN3

HSPD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPD1.

LZTS2; Smpd3; FHIT; RGS20; RGS20

Kreutmayer, S; Csordas, A; et al. Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis. CELL STRESS & CHAPERONES 18:259-268(2013).
Hjelholt, A; Carlsen, T; et al. Increased Levels of IgG Antibodies against Human HSP60 in Patients with Spondyloarthritis. PLOS ONE 8:-(2013).
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