Recombinant Human HSPD1, His-tagged

• Cat.No.: HSPD1-13997H
• Product Overview: Recombinant Human HSPD1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 225-573a.a.
• Description: This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
• Source: E.coli
• Species: Human
• Tag: His
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HSPD1 heat shock 60kDa protein 1 (chaperonin) [ Homo sapiens ]
• Official Symbol: HSPD1
• Synonyms: HSPD1; heat shock 60kDa protein 1 (chaperonin); heat shock 60kD protein 1 (chaperonin) , spastic paraplegia 13 (autosomal dominant) , SPG13; 60 kDa heat shock protein, mitochondrial; GROEL; HSP60; chaperonin 60; 60 kDa chaperonin; heat shock protein 65; P60 lymphocyte protein; mitochondrial matrix protein P1; short heat shock protein 60 Hsp60s1; HLD4; CPN60; HSP65; SPG13; HSP-60; HuCHA60
• Gene ID: 3329
• mRNA Refseq: NM_002156
• Protein Refseq: NP_002147
• MIM: 118190
• UniProt ID: P10809
• Chromosome Location: 2q33.1
• Pathway: Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; SIDS Susceptibility Pathways, organism-specific biosystem
• Function: ATP binding; ATPase activity; DNA replication origin binding; cell surface binding; chaperone binding; lipopolysaccharide binding; nucleotide binding; p53 binding; protein binding; single-stranded DNA binding; unfolded protein binding; unfolded protein bi