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Official Full Name 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Background The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.[supplied by OMIM, Oct 2009]
Synonyms HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT1DB; 5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT-1D-beta; serotonin receptor 1B; serotonin 1D beta receptor;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HTR1B-14002H Recombinant Human HTR1B, His-tagged E.coli His
    Human HTR1B-5251H Recombinant Human HTR1B Protein, GST-tagged Wheat Germ GST
    Human HTR1B-5337HCL Recombinant Human HTR1B 293 Cell Lysate HEK293 N/A
    Mouse HTR1B-7929M Recombinant Mouse HTR1B Protein Mammalian Cell His
    Rat HTR1B-2960R Recombinant Rat HTR1B Protein Mammalian Cell His
    Chicken HTR1B-4068C Recombinant Chicken HTR1B Mammalian Cell His
    Zebrafish HTR1B-6992Z Recombinant Zebrafish HTR1B Mammalian Cell His
    Kit-0996 DL-Serine Assay Kit (Fluorometric) N/A
    Kit-1350 HTR1B U2OS β-Arrestin GPCR Assay Kit N/A

    htr1b involved in several pathways and played different roles in them. We selected most pathways htr1b participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with htr1b were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway CREB3L1; NFATC1; HHIP; CALML5; CALM3; HCAR2; PRKACA; GRIA4; F2R; NPY1R
    Neuroactive ligand-receptor interaction P2RY8; ADCYAP1R1A; GNRHR2; TSHR; TAAR8C; PTGFR; DRD1A; GRIA2B; HRH4; GRIK1
    Serotonergic synapse CYP2D10; PTGS2; CYP2D9; GNGT1; HTR3A; GNAI1; HTR6; SLC6A4; HTR1E; KRAS

    htr1b has several biochemical functions, for example, drug binding, protein binding, serotonin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by htr1b itself. We selected most functions htr1b had, and list some proteins which have the same functions with htr1b. You can find most of the proteins on our site.

    Function Related Protein
    drug binding ABP1; FASN; NAMPT; CHRNB3; ACE; CHRNB4; SMO; GPR30; ADH1; CYP2C9
    protein binding LOXL3; MED23; NDUFS3; CWC22; TRIM72; FCN2; PEX14; HIPK2; FAM162A; COPS3
    serotonin binding HTR1F; MAOA; HTR1E; HTR2C; HTR2A; HTR2B; HTR3A; HTR1B
    serotonin receptor activity HTR5AL; HTR1D; HTR3B; HTR5A; HTR2A; HTR3E; HTR1E; HTR3A; HTR1B; HTR6

    htr1b has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with htr1b here. Most of them are supplied by our site. Hope this information will be useful for your research of htr1b.

    MDFI; serotonin; iodocyanopindolol/cyp; HTR1A; NME2; GSTK1

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