hyal4

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hyal4

Official Full Name hyaluronoglucosaminidase 4
Background This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity.
Synonyms HYAL4; hyaluronoglucosaminidase 4; hyaluronidase-4; hyaluronidase 4; chondroitin sulfate hydrolase; CSHY; Hyal-4; HYAL4_HUMAN; Hyaluronoglucosaminidase-4
    • Species :
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HYAL4-14021H Recombinant Human HYAL4, GST-tagged E.coli GST
    Human HYAL4-1973H Recombinant Human Hyaluronoglucosaminidase 4, His-tagged CHO His
    Human HYAL4-5218H Recombinant Human HYAL4 Protein, GST-tagged Wheat Germ GST
    Mouse HYAL4-7955M Recombinant Mouse HYAL4 Protein Mammalian Cell His

    hyal4 involved in several pathways and played different roles in them. We selected most pathways hyal4 participated on our site, such as Glycosaminoglycan degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with hyal4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan degradation GNSA; GLB1; HYAL2; SGSH; HEXA; HPSE; HGSNAT; NAGLU; IDUA; HEXB
    Metabolic pathways MTM1; PDHB; ALDH3B1; B3GALT2; LPIN1; HSD3B1; GPIB; AMPD3; ACOX3; NDUFA11

    hyal4 has several biochemical functions, for example, hyalurononglucosaminidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by hyal4 itself. We selected most functions hyal4 had, and list some proteins which have the same functions with hyal4. You can find most of the proteins on our site.

    Function Related Protein
    hyalurononglucosaminidase activity CD44; SPAM1; HYAL3; HYAL1; HYAL4; MGEA5; HYAL2; HYAL6; KIAA1199

    hyal4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with hyal4 here. Most of them are supplied by our site. Hope this information will be useful for your research of hyal4.

    Rizzardi, AE; Vogel, RI; et al. Elevated Hyaluronan and Hyaluronan-Mediated Motility Receptor Are Associated With Biochemical Failure in Patients With Intermediate-Grade Prostate Tumors. CANCER 120:1800-1809(2014).
    Shields, J; Lokeshwar, S; et al. HYAL4: A NEW HYALURONIDASE ASSOCIATED WITH BLADDER CANCER DIAGNOSIS AND PROGNOSIS. JOURNAL OF UROLOGY 191:E301-E302(2014).

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