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IFNA8

  • Official Full Name

    interferon, alpha 8

  • Overview

    Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene.
  • Synonyms

    IFNA8; interferon, alpha 8; interferon alpha-8; IFN alphaB; interferon alpha type 201; interferon alpha B; Interferon alpha B2; LeIF B; IFN-alpha-8; interferon alpha-B; interferon alpha-B2; IFN-alphaB;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • CHO
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian cells
  • C
  • His
  • mFc
  • Flag
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNA8-3219H Active Recombinant Human IFNA8 protein(Cys24-Glu189) HEK293 N/A Cys24-Glu189
Human IFNA8-341H Recombinant Human IFNA8, Gly & Pro tagged Human Cell His
Human IFNA8-45H Recombinant Human Interferon, Alpha 8 E.coli N/A
Human IFNA8-321H Active Recombinant Human IFNA8 protein, His-tagged HEK293 His Met1-Glu189
Human IFNA8-001HCL Recombinant Human IFNA8 Overexpression Lysate(Cys24-Glu189) HEK293 N/A Cys24-Glu189
Human IFNA8-1012HCL Recombinant Human IFNA8 Overexpression Lysate(Met1-Glu189) HEK293 C-His Met1-Glu189
Human IFNA8-1823HFL Recombinant Full Length Human IFNA8 Protein, C-Flag-tagged Mammalian cells Flag
Human IFNA8-1149H-B Recombinant Human IFNA8 Protein Pre-coupled Magnetic Beads HEK293
Human IFNA8-1192H Recombinant Human IFNA8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IFNA8-978H Recombinant Human IFNA8 Protein, His-tagged CHO N-His Cys24-Glu189
Human IFNA8-1149H Recombinant Human IFNA8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IFNA8-081H Recombinant Human IFNA8 Protein E.coli
Mouse IFNa8-3278M Recombinant Mouse IFNa8 protein, His-tagged HEK293 His Cys24~Glu189
Cynomolgus IFNA8-74C Active Recombinant Cynomolgus IFNA8, His tagged HEK293 His Met1-Glu189
Cynomolgus IFNA8-1022CCL Recombinant Cynomolgus IFNA8 Overexpression Lysate(Met1-Glu189) HEK293 C-His Met1-Glu189
Cynomolgus IFNA8-1035CCL Recombinant Cynomolgus IFNA8 Overexpression Lysate(Met1-Glu189) HEK293 C-mFc Met1-Glu189
Cynomolgus IFNA8-2195C Active Recombinant Cynomolgus IFNA8 protein, mFc-tagged HEK293 mFc Met1-Glu189
Cynomolgus Monkey IFNA8-73C Recombinant cynomolgus IFNA8, Fc tagged Human Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

IFNA8 involved in several pathways and played different roles in them. We selected most pathways IFNA8 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionGH2;LTBR;KDRL;IL21;INHBE;LIF;CCL18;Ccl27a;IL28A
Regulation of autophagyIFNA3;IFNPHI1;PRKAA1;IFNA1;INS1;IFNA16;Ifna11;INS2;ATG16L1
PIK-Akt signaling pathwayITGB7;Gh;GH1;RPTOR;HRAS;RAF1;G6PC2;VTN;IFNAR2
Toll-like receptor signaling pathwayMAPK11;IFNB1;TLR7;IFNAR2;MAPK8A;IFNA6;CXCL10;TLR9;PIK3R5
RIG-I-like receptor signaling pathwayRNF207B;MAPK8;CASP10;IRF3;NLRX1;IFNW1;IKBKB;IFNA2;IL12BA
Cytosolic DNA-sensing pathwayTREX1;PYCARD;IRF7;POLR2H;POLR2F;RIPK1;IFNA2;POLR3K;IL1B
Jak-STAT signaling pathwaySOCS2;IFNG1-2;CCND2;MCL1A;CCND3;IFNL3;IFNA1;GRB2B;HRAS
Natural killer cell mediated cytotoxicityIFNA7;SHC3;IFNA14;FASLG;KLRC4-KLRK1;NCR3;PRKCB;KIR2DS2;KIR3DL2
TuberculosisPPP3CB;IFNA13;CEBPG;CALM2;CAMK2A;HLA-DRB3;TNFRSF1A;IFNA4;H2-AA
Hepatitis COAS1A;EIF2AK4;IKBKE;IFNA21;CLDN16;MAPK8;CLDN6;GRB2;MAPK3
Hepatitis BCASP12;APAF1;KRAS;PRKCG;STAT5B;NFATC2;EP300;CREB3L1;CCNE1
MeaslesIFNAR1;CD209;PIK3CD;IFNA13;HSPA1A;STAT5B;EIF2AK2;Fasl;CCND3
Influenza AHSPA2;PRSS1;IVNS1ABP;NFKBIA;HLA-DRB3;NFKBIB;MAPK8;MAP2K1;MAPK1
Herpes simplex infectionTLR2-2;PER1;IKBKG;HLA-DPB1;HLA-DRB4;SRSF2B;OAS1;ARNTL;LTA
AutoiIFNA1;CD28;HLA-DRB4;GZMB;HLA-C;TSHB;HLA-DMB;CD80;CD40LG
ne thyroid diseasePRF1;Ifna11;TPO;H2-Q10;CD40LG;HLA-A;IL4;IFNA14;Il2

IFNA8 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA8 itself. We selected most functions IFNA8 had, and list some proteins which have the same functions with IFNA8. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGREM1A;GREM1;GDF1;GDF11;GM13285;CMTM5;GDF10;IFNPHI3;CMTM7
cytokine receptor bindingIFNA12;IFNPHI1;IL17F;IL17A/F3;IFNA8;IL21;IFNA14;IL15;IL15L
type I interferon receptor bindingRNF207B;Ifnz;IFNA4;IFNPHI3;IFNB1;Ifna15;Ifna11;IFNB;IFNA17

IFNA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA8.

Gene Family

Cytokines

Research Area

Related articles

Fujita, M; Scheurer, ME; et al. Role of Type 1 IFNs in Antiglioma Immunosurveillance-Using Mouse Studies to Guide Examination of Novel Prognostic Markers in Humans. CLINICAL CANCER RESEARCH 16:3409-3419(2010).
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