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Official Full Name interferon, alpha 8
Background Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene.
Synonyms IFNA8; interferon, alpha 8; interferon alpha-8; IFN alphaB; interferon alpha type 201; interferon alpha B; Interferon alpha B2; LeIF B; IFN-alpha-8; interferon alpha-B; interferon alpha-B2; IFN-alphaB
    • Species :
    • Cynomolgus Monkey
    • Human
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Human Cell
    • Tag :
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IFNA8-081H Recombinant Human IFNA8 Protein E. coli
    Human IFNA8-001HCL Recombinant Human IFNA8 cell lysate Human Cell N/A
    Human IFNA8-1012HCL Recombinant Human IFNA8 cell lysate Human Cell N/A
    Human IFNA8-1192H Recombinant Human IFNA8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human IFNA8-321H Recombinant Human IFNA8, His-tagged Human Cell His
    Human IFNA8-341H Recombinant Human IFNA8, Gly & Pro tagged Human Cell His
    Human IFNA8-45H Recombinant Human Interferon, Alpha 8 E.coli N/A
    Cynomolgus Monkey IFNA8-1022CCL Recombinant Cynomolgus IFNA8 cell lysate Human Cell N/A
    Cynomolgus Monkey IFNA8-1035CCL Recombinant Cynomolgus IFNA8 cell lysate Human Cell N/A
    Cynomolgus Monkey IFNA8-73C Recombinant cynomolgus IFNA8, Fc tagged Human Cell His
    Cynomolgus Monkey IFNA8-74C Recombinant Cynomolgus IFNA8, His tagged Human Cell His

    ifna8 involved in several pathways and played different roles in them. We selected most pathways ifna8 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ifna8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CSF3; BMP7A; GM1987; IL-15RA; FIGF; KIT; PRLR; NGFRB; CD40LG; LIFRA
    Regulation of autophagy ATG12; ATG10; ULK3; BECN1; Ifna15; ATG4C; Ifna11; IFNA8; ULK2; IFNA2
    PIK-Akt signaling pathway ITGA1; ITGA2B; NFKB1; IBSP; YWHAH; LAMC2; FGF5; ITGA6; SOS1; LAMA4
    Toll-like receptor signaling pathway IFNA4; IL-8; IL12B; IFNB1; IFNA21; MAPK1; TICAM2; PIK3R3; STAT1A; TLR2-1
    RIG-I-like receptor signaling pathway RELA; IRF3; NFKBIAA; NFKBIB; IFNA1; CXCL8B.3; IFNB1; MAPK8A; IFNA8; MAPK14B
    Cytosolic DNA-sensing pathway POLR2L; CCL4L2; POLR3D; AIM2; IFNA1; NFKBIAA; IFNA6; CXCL10; RELA; POLR3F
    Jak-STAT signaling pathway IL11; CNTFR; IL2RB; EP300; Il23a; IFNL3; GM-CSF; AKT1; SOS1; RNF207B
    Natural killer cell mediated cytotoxicity BID; ULBP1; RAET1E; KIR3DL1; PTPN11; FYN; FCGR3; RAET1L; RAET1G; RAC2
    Tuberculosis CD14; IL12A; CD209C; PPP3CC; IFNA4; CLEC7A; ITGAM; CARD9; CD74; HLA-DOB
    Hepatitis B IRF3; TGFBR1; Fasl; SMAD4; MAPK1; PIK3R5; MYD88; STAT5A; EGR2; STAT1
    Measles PIK3R5; FAS; RAB9A; IFNAR1; CD3G; MAVS; HSPA6; IFNA13; TAB2; STAT2
    Influenza A VDAC1; IFNA1; IL1A; MAPK1; DNAJB1; MAPK12; PIK3CA; IFNA16; PRSS1; TRIM25
    Herpes simplex infection BF2; PER1A; EEF1D; IFNA7; TAF4B; TNFSF14; ARNTL; IFNA4; BF1; H2-AA
    ne thyroid disease TSHB; IFNA8; HLA-DMA; IFNA4; H2-Q10; IFNA17; HLA-DQA2; Il2; HLA-DRA; Ifna11

    ifna8 has several biochemical functions, for example, cytokine activity, cytokine receptor binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ifna8 itself. We selected most functions ifna8 had, and list some proteins which have the same functions with ifna8. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity VEGFA; IFNA21; WNT7A; IL1A; KITLG; TGFB3; GDF7; LTA; BMP8A; IL8L2
    cytokine receptor binding IFNA14; IL17F; MIF; Ifna11; IFNA12; IFNPHI3; IFNPHI4; IL17D; IFN-a; IFNA21
    type I interferon receptor binding IFNA2; IFNA4; IFNA1; IFNA21; IFNA16; GM13288; GM13285; IFNB; IFNA7; IFNA8

    ifna8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ifna8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ifna8.

    Fujita, M; Scheurer, ME; et al. Role of Type 1 IFNs in Antiglioma Immunosurveillance-Using Mouse Studies to Guide Examination of Novel Prognostic Markers in Humans. CLINICAL CANCER RESEARCH 16:3409-3419(2010).

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