IFNA8
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Official Full Name
interferon, alpha 8 -
Overview
Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene. -
Synonyms
IFNA8;interferon, alpha 8;interferon alpha-8;IFN alphaB;interferon alpha type 201;interferon alpha B;Interferon alpha B2;LeIF B;IFN-alpha-8;interferon alpha-B;interferon alpha-B2;IFN-alphaB
Recombinant Proteins
- Cynomolgus
- Human
- Mouse
- HEK293
- Human Cells
- E.coli
- Mammalian Cells
- CHO
- His
- Non
- mFc
- Avi
- Fc
- Flag
Involved Pathway
IFNA8 involved in several pathways and played different roles in them. We selected most pathways IFNA8 participated on our site, such as Cytokine-cytokine receptor interaction,Regulation of autophagy,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IFNA8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Autoi | TPO,H2-Q10,H2-AA,IFNA14,HLA-DRB1,HLA-DPA1,IFNA2,IFNA1,IL5,IFNA4 |
| Natural killer cell mediated cytotoxicity | KIR2DS3,IFNA17,VAV3,KLRA8,SH2D1B,NRAS,BID,TNFRSF10A,PTK2B,ITGB2 |
| Measles | PIK3CA,PRKCQ,IFNGR2,CCNE2,EIF2AK4,IFNA16,PIK3CD,CBLB,IL12A,HSPA1B |
| Influenza A | TLR7,HLA-DOB,IFNAR2,AKT1,Ifna15,TNFRSF10C,IFNA17,H2-AA,IFNA7,HLA-DQA2 |
| Hepatitis B | AKT1,STAT6,PIK3CA,SMAD4,APAF1,IRF7,CASP9,RELA,MAPK10,IFN-a |
| Toll-like receptor signaling pathway | CCL3L1,MAPK9,STAT1A,CD80,IFNA17,IFNA12,PIK3CG,MAP2K4,PIK3R5,IFNA4 |
| Cytosolic DNA-sensing pathway | CCL5,IFNA3,POLR1D,ADAR,CXCL10,Ifna11,TMEM173,IFNA13,POLR3E,POLR2K |
| Herpes simplex infection | MHC2DAB,HLA-DRA,PVRL1B,EEF1D,Ifna11,TAF3,EIF2AK2,TAB2,SRSF3,BMA2 |
| PIK-Akt signaling pathway | Pdgfa&Pdgfb,NOS3,PIK3CD,PPP2R5D,IFNA2,G6PC2,LPAR4,PKN3,FGF16,MCL1 |
Protein Function
IFNA8 has several biochemical functions, for example, cytokine activity,cytokine receptor binding,type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IFNA8 itself. We selected most functions IFNA8 had, and list some proteins which have the same functions with IFNA8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | CMTM4,NAMPT,INHA,GRN,TNFSF10,MSTN,IFNPHI1,CMTM2,IFN-a,CMTM1 |
| type I interferon receptor binding | GM13278,IFNA12,IFNPHI4,IFNPHI1,IFNB1,RNF207B,IFNA14,IFNA16,OSTN,IFNA7 |
| cytokine receptor binding | IL17A/F2,IL15,IFNA14,IL17B,IL17A,IL17A/F1,IFNA3,IL15L,IFNPHI2,IFNA13 |
Interacting Protein
IFNA8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IFNA8 here. Most of them are supplied by our site. Hope this information will be useful for your research of IFNA8.
Resources
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References
- Fujita, M; Scheurer, ME; et al. Role of Type 1 IFNs in Antiglioma Immunosurveillance-Using Mouse Studies to Guide Examination of Novel Prognostic Markers in Humans. CLINICAL CANCER RESEARCH 16:3409-3419(2010).
