IL12RB1 involved in several pathways and played different roles in them. We selected most pathways IL12RB1 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with IL12RB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Cytokine-cytokine receptor interaction |
CSF2RB; CCL5; LEPB; CCR6A; IL19; LEPA; CXCR2; CTF1; KITLGB; CCL4 |
| Jak-STAT signaling pathway |
IL2RB; PIK3R1; AOX3L1; STAT3; HRASB; BCL2L1; IRX1; GM2002; IFNA13; CTF1 |
| Inflammatory bowel disease (IBD) |
TLR5; HLA-DQA2; IL1A; HLA-DMA; IFNGR1; IL2RG; TGFB3; IL21R; IL4; Il4ra |
IL12RB1 has several biochemical functions, for example, cytokine receptor activity, contributes_to interleukin-12 receptor activity, contributes_to interleukin-12 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL12RB1 itself. We selected most functions IL12RB1 had, and list some proteins which have the same functions with IL12RB1. You can find most of the proteins on our site.
| Function |
Related Protein |
| cytokine receptor activity |
F3A; CRFB15; IL31RA; F3; LIFRB; CRFB2; Ifnlr1; Il4ra; GHRA; IL15RA |
| contributes_to interleukin-12 receptor activity |
IL12RB1 |
| contributes_to interleukin-12 receptor binding |
IL23R; IL12B; IL12RB1 |
| contributes_to interleukin-23 binding |
IL12RB1; IL23R |
| contributes_to interleukin-23 receptor activity |
IL23R; IL12RB1 |
IL12RB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL12RB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL12RB1.
IL12A; IL12B; SNRPD3; il23a_il-12b_human
Famulski, KS; Reeve, J; et al. Kidney Transplants With Progressing Chronic Diseases Express High Levels of Acute Kidney Injury Transcripts. AMERICAN JOURNAL OF TRANSPLANTATION 13:634-644(2013).
Tang, SW; Yang, TC; et al. Nicotinamide N-methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells. CARCINOGENESIS 32:138-145(2011).
