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Recombinant Human IL12RB1 protein, hFc-Avi-tagged

Cat.No. : IL12RB1-6332H
Product Overview : Recombinant Human IL12RB1 protein(P42701)(24-545aa), fused with C-hFc-Avi tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : hFc-Avi
Protein length : 24-545a.a.
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 85.5 kDa
AASequence : CRTSECCFQDPPYPDADSGSASGPR DLRCYRISSDRYECSWQYEGPTAGV SHFLRCCLSSGRCCYFAAGSATRLQ FSDQAGVSVLYTVTLWVESWARNQT EKSPEVTLQLYNSVKYEPPLGDIKV SKLAGQLRMEWETPDNQVGAEVQFR HRTPSSPWKLGDCGPQDDDTESCLC PLEMNVAQEFQLRRRQLGSQGSSWS KWSSPVCVPPENPPQPQVRFSVEQL GQDGRRRLTLKEQPTQLELPEGCQG LAPGTEVTYRLQLHMLSCPCKAKAT RTLHLGKMPYLSGAAYNVAVISSNQ FGPGLNQTWHIPADTHTEPVALNIS VGTNGTTMYWPARAQSMTYCIEWQP VGQDGGLATCSLTAPQDPDPAGMAT YSWSRESGAMGQEKCYYITIFASAH PEKLTLWSTVLSTYHFGGNASAAGT PHHVSVKNHSLDSVSVDWAPSLLST CPGVLKEYVVRCRDEDSKQVSEHPV QPTETQVTLSGLRAGVAYTVQVRAD TAWLRGVWSQPQRFSIEVQVSD
Purity : Greater than 85% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.
Gene Name : IL12RB1 interleukin 12 receptor, beta 1 [ Homo sapiens ]
Official Symbol : IL12RB1
Synonyms : IL12RB1; interleukin 12 receptor, beta 1; IL12RB; interleukin-12 receptor subunit beta-1; CD212; IL-12RB1; IL-12R-beta-1; IL-12R subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; interleukin-12 receptor beta-1 chain; IL-12R-BETA1; MGC34454;
Gene ID : 3594
mRNA Refseq : NM_005535
Protein Refseq : NP_005526
MIM : 601604
UniProt ID : P42701

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
04/06/2022

    Reliable in co-immunoprecipitation.

    10/18/2021

      Effective in asthma models.

      12/21/2017

        great in Western blot analysis.

        Q&As (10)

        Ask a question
        Could you explain the significance of CRISPR/Cas9-mediated gene tagging in tracking IL12RB1 localization? 09/18/2021

        Gene tagging allows real-time tracking of IL12RB1 subcellular localization.

        Can you elaborate on the use of RNA-seq analysis to profile gene expression changes upon IL12RB1 activation? 07/02/2021

        RNA-seq profiles gene expression changes upon IL12RB1 activation.

        What are the applications of ChIP-seq in exploring IL12RB1's role in gene regulation? 01/23/2021

        ChIP-seq investigates IL12RB1's impact on gene regulation networks.

        What methods can be employed to assess IL12RB1 dimerization and its effect on downstream signaling? 06/13/2020

        Crosslinking and immunoprecipitation assess IL12RB1 dimerization and signaling.

        What techniques are suitable for studying IL12RB1's interaction with IL12A and IL23A? 02/14/2020

        Co-immunoprecipitation and ELISA assay IL12RB1 interactions with cytokines.

        How can the role of IL12RB1 in signal transduction be elucidated using knockdown experiments? 12/27/2019

        Knockdown experiments reveal IL12RB1's contribution to signal transduction.

        What are the advantages of using siRNA screening to identify IL12RB1-regulated pathways? 02/22/2019

        siRNA screening identifies pathways influenced by IL12RB1 expression.

        How do co-crystallization studies aid in understanding the molecular details of IL12RB1 interactions? 01/02/2019

        Co-crystallization offers structural insights into IL12RB1 interactions.

        How does flow cytometry provide insights into IL12RB1 expression levels on different cell types? 10/26/2018

        Flow cytometry quantifies IL12RB1 levels on diverse cell populations.

        What experimental approaches validate IL12RB1's involvement in cytokine-mediated immune responses? 06/25/2018

        Functional assays validate IL12RB1's role in immune responses.

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