Recombinant Human IL12RB1 Protein, His-tagged
Cat.No. : | IL12RB1-074H |
Product Overview : | Recombinant Human IL12RB1 Protein with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | ~52 kDa |
AA Sequence : | CRTSECCFQDPPYPDADSGSASGPR DLRCYRISSDRYECSWQYEGPTAGV SHFLRCCLSSGRCCYFAAGSATRLQ FSDQAGVSVLYTVTLWVESWARNQT EKSPEVTLQLYNSVKYEPPLGDIKV SKLAGQLRMEWETPDNQVGAEVQFR HRTPSSPWKLGDCGPQDDDTESCLC PLEMNVAQEFQLRRRQLGSQGSSWS KWSSPVCVPPENPPQPQVRFSVEQL GQDGRRRLTLKEQPTQLELPEGCQG LAPGTEVTYRLQLHMLSCPCKAKAT RTLHLGKMPYLSGAAYNVAVISSNQ FGPGLNQTWHIPADTHTEPVALNIS VGTNGTTMYWPARAQSMTYCIEWQP VGQDGGLATCSLTAPQDPDPAGMAT YSWSRESGAMGQEKCYYITIFASAH PEKLTLWSTVLSTYHFGGNASAAGT PHHVSVKNHSLDSVSVDWAPSLLST CPGVLKEYVVRCRDEDSKQVSEHPV QPTETQVTLSGLRAGVAYTVQVRAD TAWLRGVWSQPQRFSIEVQVSD |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | IL12RB1 interleukin 12 receptor, beta 1 [ Homo sapiens (human) ] |
Official Symbol : | IL12RB1 |
Synonyms : | IL12RB1; interleukin 12 receptor, beta 1; IL12RB; interleukin-12 receptor subunit beta-1; CD212; IL-12RB1; IL-12R-beta-1; IL-12R subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; interleukin-12 receptor beta-1 chain; IL-12R-BETA1; MGC34454; |
Gene ID : | 3594 |
mRNA Refseq : | NM_005535 |
Protein Refseq : | NP_005526 |
MIM : | 601604 |
UniProt ID : | P42701 |
Products Types
◆ Recombinant Protein | ||
IL12RB1-4306H | Recombinant Human IL12RB1 protein, His-tagged | +Inquiry |
IL12RB1-6332H | Recombinant Human IL12RB1 protein, hFc-Avi-tagged | +Inquiry |
IL12RB1-4432H | Recombinant Human IL12RB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il12rb1-1238M | Recombinant Mouse Il12rb1 Protein, MYC/DDK-tagged | +Inquiry |
Il12rb1-10576M | Recombinant Mouse Il12rb1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL12RB1-2188HCL | Recombinant Human IL12RB1 cell lysate | +Inquiry |
Related Gene
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewReliable in co-immunoprecipitation.
Effective in asthma models.
great in Western blot analysis.
Q&As (10)
Ask a questionGene tagging allows real-time tracking of IL12RB1 subcellular localization.
RNA-seq profiles gene expression changes upon IL12RB1 activation.
ChIP-seq investigates IL12RB1's impact on gene regulation networks.
Crosslinking and immunoprecipitation assess IL12RB1 dimerization and signaling.
Co-immunoprecipitation and ELISA assay IL12RB1 interactions with cytokines.
Knockdown experiments reveal IL12RB1's contribution to signal transduction.
siRNA screening identifies pathways influenced by IL12RB1 expression.
Co-crystallization offers structural insights into IL12RB1 interactions.
Flow cytometry quantifies IL12RB1 levels on diverse cell populations.
Functional assays validate IL12RB1's role in immune responses.
Ask a Question for All IL12RB1 Products
Required fields are marked with *
My Review for All IL12RB1 Products
Required fields are marked with *
Inquiry Basket