IL17D
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Official Full Name
interleukin 17D
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Background
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008] -
Synonyms
IL17D; interleukin 17D; IL27; IL-27; IL-17D; interleukin-17D; interleukin 27;
- Involved Pathway
- Protein Function
- Interacting Protein
- IL17D Related Gene Family
- IL17D Related Research Area
IL17D involved in several pathways and played different roles in them. We selected most pathways IL17D participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL17D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Jak-STAT signaling pathway | CCND1;IL20;MCL1A;OSM;PIAS2;SOCS6;AKT2;EP300;GM2002 |
IL17D has several biochemical functions, for example, cytokine activity, cytokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL17D itself. We selected most functions IL17D had, and list some proteins which have the same functions with IL17D. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytokine activity | CMTM8;IFNPHI2;GREM1A;IL36A;CSF1;IL17D;ADIPOQ;SPAW;IL13 |
| cytokine receptor binding | IL17F;IFNA3;IL17A;IFNT2;IL15;IFNA14;IL17A/F1;IFNW1;IFNPHI3 |
IL17D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL17D here. Most of them are supplied by our site. Hope this information will be useful for your research of IL17D.
- Q&As
- Reviews
Q&As (10)
Ask a questionNeuroinflammation models, neuronal cell assays, and CNS analysis explore IL17D's role in neurological contexts.
Tumor xenografts, immune cell infiltration analysis, and gene expression profiling dissect IL17D's role in cancer.
Functional assays, knockout models, and gene expression analyses distinguish IL17D's unique roles.
Microbiota sequencing, gnotobiotic models, and immune cell profiling investigate IL17D-gut microbiota interactions.
Animal models, patient samples, and genetic studies elucidate IL17D's involvement in autoimmune diseases.
Wound healing assays, tissue regeneration studies, and histological analyses examine IL17D's effects on tissue repair.
Signal transduction assays, phosphoproteomics, and cytokine profiling reveal IL17D's signaling pathways.
Cell culture models, infection assays, and epithelial barrier assessments uncover IL17D's impact on host defense.
Flow cytometry, chemotaxis assays, and adoptive transfer experiments probe IL17D-mediated immune responses.
Therapeutic antibody testing, RNA interference, and animal disease models validate IL17D as a potential therapy.
Customer Reviews (3)
Write a reviewEffective in Th9 differentiation. -
Suitable for ELISA. -
High bioactivity. -
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