Active Recombinant Human IL17D protein IL17D-128H

Active Recombinant Human IL17D protein


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Cat.No. : IL17D-128H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL17D was expressed in E. coli.
Description : Interleukin 17D is a disulfide-linked homodimer belonging to the IL-17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17D induces expression of endothelial IL6, IL8, and GM-CSF, and inhibits hemopoiesis of myeloid progenitor cells.
Source : E. coli
Species : Human
Form : Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA (with BSA as a carrier protein)
Bio-activity : The ED50 is 7.5-37.5 ng/mL as determined by its binding ability in a functional ELISA (at a concentration of 1 μg/mL).
Molecular Mass : 20.5 kDa
Endotoxin : <1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity : >95%
Applications : Cell Assay
Storage : The lyophilized protein is stable for at least one year from date of receipt at -70 centigrade. Upon reconstitution, this cytokine can be stored in working aliquots at 2 centigrade - 8 centigrade for one month, or at -20 centigrade for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Reconstitution : Reconstitute in sterile 4mM HCl at 100μg/mL (containing at least 0.1% human or bovine serum albumin)
Figure :

Gene Name : IL17D interleukin 17D [ Homo sapiens ]
Official Symbol : IL17D
Synonyms : IL17D; interleukin 17D; interleukin-17D; FLJ30846; IL 17D; IL 22; IL 27; IL27; interleukin 27; interleukin-27; IL-22; IL-27; IL-17D;
Gene ID : 53342
mRNA Refseq : NM_138284
Protein Refseq : NP_612141
MIM : 607587
UniProt ID : Q8TAD2
Chromosome Location : 13q11
Function : cytokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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