IL17D-167H
Optional Service: Optional requirements on this protein
Product Overview :
Recombinant Human IL-17D produced inE.coliis a disulfide-linked homodimer with a total weight of 40.5 kDa, consisting of 370 amino acid residues.
Description :
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays.
Source :
E.coli.
Purity :
> 98% by SDS-PAGE and HPLC analysis.
Endotoxin Level :
< 0.1 ng per ug of IL-17D.
Stabilizer :
None.
Formulation :
Lyophilized.
Biological Activity :
Testing in progress.
Reconstitution :
The human IL-17D should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃.
Stability :
The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17D should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.