Recombinant Human Interleukin 17D
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Cat.No. : | IL17D-167H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human IL-17D produced inE.coliis a disulfide-linked homodimer with a total weight of 40.5 kDa, consisting of 370 amino acid residues. |
Description : | The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. |
Source : | E.coli. |
Purity : | > 98% by SDS-PAGE and HPLC analysis. |
Endotoxin Level : | < 0.1 ng per ug of IL-17D. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biological Activity : | Testing in progress. |
Reconstitution : | The human IL-17D should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃. |
Stability : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17D should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles. |
Gene Name : | IL17D interleukin 17D [ Homo sapiens ] |
Synonyms : | IL17D; interleukin 17D;IL27; IL-22; IL-27; IL-17D; FLJ30846; interleukin 27; Interleukin-17D; Interleukin-27; OTTHUMP00000018104 |
Gene ID : | 53342 |
mRNA Refseq : | NM_138284 |
Protein Refseq : | NP_612141 |
MIM : | 607587 |
UniProt ID : | Q8TAD2 |
Chromosome Location : | 13q11 |
Function : | cytokine activity |
◆ Recombinant Protein
Il17d-1664M | Recombinant Mouse Il17d Protein, His-tagged | +Inquiry |
IL17D-5206H | Recombinant Human IL17D Protein, GST-tagged | +Inquiry |
IL17D-14155H | Recombinant Human IL17D, GST-tagged | +Inquiry |
IL17D-7978H | Recombinant Human IL17D protein, His & GST-tagged | +Inquiry |
IL17D-129H | Recombinant Human IL17D protein | +Inquiry |
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◆ Lysates
IL17D-852HCL | Recombinant Human IL17D cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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