Recombinant Human Interleukin 17D IL17D-167H

Recombinant Human Interleukin 17D


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Recombinant Human Interleukin 17D

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Cat.No. : IL17D-167H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human IL-17D produced inE.coliis a disulfide-linked homodimer with a total weight of 40.5 kDa, consisting of 370 amino acid residues.
Description : The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 155 amino acid chains, secreted by activated T-cells and acts on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region and differ from one another in their N-terminal segments and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as disulfide-linked homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8 and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays.
Source : E.coli.
Purity : > 98% by SDS-PAGE and HPLC analysis.
Endotoxin Level : < 0.1 ng per ug of IL-17D.
Stabilizer : None.
Formulation : Lyophilized.
Biological Activity : Testing in progress.
Reconstitution : The human IL-17D should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃.
Stability : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17D should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.
Gene Name : IL17D interleukin 17D [ Homo sapiens ]
Synonyms : IL17D; interleukin 17D;IL27; IL-22; IL-27; IL-17D; FLJ30846; interleukin 27; Interleukin-17D; Interleukin-27; OTTHUMP00000018104
Gene ID : 53342
mRNA Refseq : NM_138284
Protein Refseq : NP_612141
MIM : 607587
UniProt ID : Q8TAD2
Chromosome Location : 13q11
Function : cytokine activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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