| Cat. No. : |
Il17d-645M |
| Description : |
TheInterleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17Bthrough IL-17F), are secreted, structurally related proteins that share a conservedcysteine-knot fold near the C-terminus, but have considerable sequencedivergence at the N-terminus. With the exception of IL-17B, which exists as anon-covalently linked dimer, all IL-17 family members are disulfide-linked dimers.IL17 family proteins are pro-inflammatory cytokines that induce localcytokine production and are involved in the regulation of immune functions. |
| Source : |
E. coli |
| Form : |
Lyophilizedfrom a 0.2 um filtered solution in Acetonitrile and TFA with BSA as a carrierprotein. |
| N-terminalSequence : |
Ala25 |
| MolecularWeight : |
20 kDa (monomer) |
| Activity : |
Measuredby its ability to bind rmIL17-BR/Fc Chimera in a functional ELISA. |
| Endotoxin Level : |
<1.0EU per 1μg of the protein by the LAL method. |
| Purity : |
>95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Reconstitution : |
Reconstituteat 100μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovineserum albumin. |
| Storage : |
Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
