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INVS

  • Official Full Name

    inversin

  • Overview

    This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2012]
  • Synonyms

    INVS; inversin; INV; NPH2; NPHP2; nephrocystin-2; inversion of embryonic turning; inversion of embryo turning homolog;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human INVS-395H Recombinant Human INVS Mammalian Cell His
Human INVS-7870H Recombinant Human INVS protein, His & T7-tagged E.coli His/T7 Met1~Val237 (Accession # Q9Y283)
Human INVS-3165H Recombinant Human INVS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human INVS-5082H Recombinant Human INVS Protein, GST-tagged Wheat Germ GST
Human INVS-3165H-B Recombinant Human INVS Protein Pre-coupled Magnetic Beads HEK293
Human INVS-5686HF Recombinant Full Length Human INVS Protein, GST-tagged In Vitro Cell Free System GST 101 amino acids
Human INVS-3510H Recombinant Human INVS Protein (Met1-Lys91), N-GST tagged E.coli N-GST Met1-Lys91
Mouse Invs-2331M Recombinant Mouse Invs Protein, His-tagged E.coli N-His Met1-Val239
Zebrafish INVS-9436Z Recombinant Zebrafish INVS Mammalian Cell His
Chicken INVS-6120C Recombinant Chicken INVS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • INVS Related Articles

INVS involved in several pathways and played different roles in them. We selected most pathways INVS participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with INVS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayCAMK2G;NLK;WNT4A;INVS;TBL1X;MAPK8A;SFRP4;DAAM1B;FZD3B

INVS has several biochemical functions, for example, calmodulin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by INVS itself. We selected most functions INVS had, and list some proteins which have the same functions with INVS. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingDCX;GM101;MAPKAPK2B;TJP1;NOS2;NETO2;CDK5RAP2;CAMKK1;MYO5B
protein bindingACVR1L;ACTL6A;EGR2;NPDC1;OTULIN;ADORA1;ARHGAP24;METTL1;TFB1M

INVS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with INVS here. Most of them are supplied by our site. Hope this information will be useful for your research of INVS.

Widman, DG; Frolov, I; et al. Third-Generation Flavivirus Vaccines Based on Single-Cycle, Encapsidation-Defective Viruses. ADVANCES IN VIRUS RESEARCH, VOL 72 72:77-126(2008).
SODEIK, B; DOMS, RW; et al. ASSEMBLY OF VACCINIA VIRUS - ROLE OF THE INTERMEDIATE COMPARTMENT BETWEEN THE ENDOPLASMIC-RETICULUM AND THE GOLGI STACKS. JOURNAL OF CELL BIOLOGY 121:521-541(1993).
  • Q&As
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