Recombinant Human INVS Protein, GST-tagged

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Recombinant Human INVS Protein, GST-tagged

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Cat.No. : INVS-5082H
Product Overview : Human INVS full-length ORF ( AAH06370, 1 a.a. - 101 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.85 kDa
AA Sequence : MNKSENLLFA GSSLASQVHA AAVNGDKGAL QRLIVGNSAL KDKEDQFGRT PLMYCVLADR LDCADALLKA GADVNKTDHS QRTALHLAAQ KALRTISTGR I
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : INVS inversin [ Homo sapiens ]
Official Symbol : INVS
Synonyms : INVS; inversin; nephronophthisis 2 (infantile) , NPHP2; nephrocystin 2; nephrocystin-2; inversion of embryonic turning; inversion of embryo turning homolog; INV; NPH2; NPHP2; KIAA0573; MGC133080; MGC133081;
Gene ID : 27130
mRNA Refseq : NM_014425
Protein Refseq : NP_055240
MIM : 243305
UniProt ID : Q9Y283

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