Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

ITPK1

Official Full Name

inositol-tetrakisphosphate 1-kinase
Overview

Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene.
Synonyms

ITPK1; inositol-tetrakisphosphate 1-kinase; inositol 1,3,4 triphosphate 5/6 kinase; ins(1,3,4)P(3) 5/6-kinase; inositol-triphosphate 5/6-kinase; inositol 1,3,4-triphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6 kinase; inositol 1,3,4-trisphosphate;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ITPK1-1351H	Recombinant Human Inositol-Tetrakisphosphate 1-kinase, His-tagged	E.coli	His	1-414aa	Inquiry
Human	ITPK1-5112HCL	Recombinant Human ITPK1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ITPK1-4950H	Recombinant Human ITPK1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ITPK1-5838HF	Recombinant Full Length Human ITPK1 Protein, GST-tagged	In Vitro Cell Free System	GST	314 amino acids	Inquiry
Human	ITPK1-3757H	Recombinant Human ITPK1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	ITPK1-8385M	Recombinant Mouse ITPK1 Protein	Mammalian Cell	His		Inquiry
Mouse	ITPK1-4652M-B	Recombinant Mouse ITPK1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	ITPK1-4652M	Recombinant Mouse ITPK1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Itpk1-3619M	Recombinant Mouse Itpk1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Chicken	ITPK1-1959C	Recombinant Chicken ITPK1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
ITPK1 Related Articles

ITPK1 involved in several pathways and played different roles in them. We selected most pathways ITPK1 participated on our site, such as 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian), 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3), D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)	ITPK1;ITPKB;ITPKA
1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)
D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis
D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis
Factors involved in megakaryocyte development and platelet production	BA1;IRF2;DOCK11;HBB-BH1;KDM1A;CENPE;KIF9;VPS45;D-AKAP2
Hemostasis	DOCK2;ANXA2B;F11R.2;KIF2A;MMRN2A;KIF4A;ITGB3A;HBB-Y;DOCK10
Inositol phosphate metabolism	PLCD1A;IMPA1;NUDT11;PLD4;PTENB;MTMR7;PI4KAA;PLCD4;MTMR6
Metabolic pathways	GBGT1;PISD;POLR3D;B4GALT4;KDSR;UGT1A6B;OAT;B3GNT1;PIGO

ITPK1 has several biochemical functions, for example, ATP binding, catalytic activity, inositol tetrakisphosphate 1-kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPK1 itself. We selected most functions ITPK1 had, and list some proteins which have the same functions with ITPK1. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MAP3K8;ADCK2;PRKACG;DNAJA3;P2RX3B;ACSL4;CKMT2A;ACTB2;KIF16B
catalytic activity	Acsm2a;PNP4B;AADAC;PFKMA;PGGT1B;SYN3;ACCSL;TDH;PPM1DA
inositol tetrakisphosphate 1-kinase activity	ITPK1A;ITPK1
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	SACM1LB;PTPRQ;CTDSPL2A;TENC1;SGPP2;CTDSPL2B;ITPK1;NT5DC3;SACM1L
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	SACM1LA;PXYLP1;PTPRQ;TENC1;SACM1L;ITPK1;SGPP2;NT5DC3;SACM1LB
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	CTDSPL2B;SGPP2;SACM1LB;NT5DC3;TENC1;SACM1L;CTDSPL2A;PXYLP1;PTPRQ
inositol-1,3,4-trisphosphate 5-kinase activity	ITPK1A;ITPK1
inositol-1,3,4-trisphosphate 6-kinase activity	ITPK1A;ITPK1
inositol-3,4,6-trisphosphate 1-kinase activity
isomerase activity	PBLD1;PPIFB;ITPK1;PPIFA;TSTA3;HSD17B4;FKBP10B;TPI1B;PPIAB
magnesium ion binding	RPS6KA3B;PCK1;PSPH;SPHK1;MAST4;PGM1;ABL2;NME1;MTHFD2

ITPK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPK1.

TRAF2; pi3p; CDC5L

Guan, Z; Wang, JH; et al. The Maternal ITPK1 Gene Polymorphism Is Associated with Neural Tube Defects in a High-Risk Chinese Population. PLOS ONE 9:-(2014).

Porcu, E; Medici, M; et al. A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function. PLOS GENETICS 9:-(2013).