Recombinant Human ITPK1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ITPK1-3757H
• Product Overview: ITPK1 MS Standard C13 and N15-labeled recombinant protein (NP_001136065) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.6 kDa
• AA Sequence: MQTFLKGKRVGYWLSEKKIKKLNFQ AFAELCRKRGMEVVQLNLSRPIEEQ GPLDVIIHKLTDVILEADQNDSQSL ELVHRFQEYIDAHPETIVLDPLPAI RTLLDRSKSYELIRKIEAYMEDDRI CSPPFMELTSLCGDDTMRLLEKNGL TFPFICKTRVAHGTNSHEMAIVFNQ EGLNAIQPPCVVQNFINHNAVLYKV FVVGESYTVVQRPSLKNFSAGTSDR ESIFFNSHNVSKPESSSVLTELDKI EGVFERPSDEVIRELSRALRQALGV SLFGIDIIINNQTGQHAVIDINAFP GYEGVSEFFTDLLNHIATVLQGQST AMAATGDVALLRHSKLLAEPAGGLV GERTCSASPGCCGSMMGQDAPWKAE ADAGGTAKLPHQRLGCNAGVSPSFQ QHCVASLATKASSQTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ITPK1 inositol-tetrakisphosphate 1-kinase [ Homo sapiens (human) ]
• Official Symbol: ITPK1
• Synonyms: ITPK1; inositol-tetrakisphosphate 1-kinase; inositol 1,3,4 triphosphate 5/6 kinase; ins(1,3,4)P(3) 5/6-kinase; inositol-triphosphate 5/6-kinase; inositol 1,3,4-triphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6 kinase; inositol 1,3,4-trisphosphate 5/6-kinase; ITRPK1
• Gene ID: 3705
• mRNA Refseq: NM_001142593
• Protein Refseq: NP_001136065
• MIM: 601838
• UniProt ID: Q13572